TREM1

Gene Symbol	TREM1
Entrez Gene	54210
Alt Symbol	CD354, TREM-1
Species	Human
Gene Type	protein-coding
Description	triggering receptor expressed on myeloid cells 1
Other Description	triggering receptor expressed on monocytes 1|triggering-receptor TREM1
Swissprots	B4DWG2 Q5T2C9 K7EJW1 Q9NP99 Q86YU1 Q53FL8
Accessions	ABB01010 CAJ78384 EAX04043 EAX04044 Q9NP99 AF196329 AAF71694 AF287008 AAF90197 AK130673 AK223264 BAD96984 AK292162 BAF84851 AK301519 BAG63024 AK313104 BAG35927 AY074783 AAL74018 BC017773 AAH17773 DA362458 DA938757 DQ892009 ABM82935 DQ895198 ABM86124 XM_006715117 XP_006715180 XM_011514696 XP_011512998 XM_011514697 XP_011512999 NM_001242589 NP_001229518 NM_001242590 NP_001229519 NM_018643 NP_061113
Function	Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock. {ECO:0000269|PubMed:10799849, ECO:0000269|PubMed:11323674}.
Subcellular Location	Isoform 1: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity	Highly expressed in adult liver, lung and spleen than in corresponding fetal tissue. Also expressed in the lymph node, placenta, spinal cord and heart tissues. Expression is more elevated in peripheral blood leukocytes than in the bone marrow and in normal cells than malignant cells. Expressed at low levels in the early development of the hematopoietic system and in the promonocytic stage and at high levels in mature monocytes. Strongly expressed in acute inflammatory lesions caused by bacteria and fungi. Isoform 2 was detected in the lung, liver and mature monocytes. {ECO:0000269|PubMed:10799849, ECO:0000269|PubMed:11922939}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

soluble TREM1 Human SimpleStep ELISA™ Kit - ab185987 from Abcam Category ELISA Kit Prices $484.00 Sizes 1 x 96 tests Sensitivity 154 pg/ml Range 500 pg/ml - 32000 pg/ml

TREM1 Human ELISA Kit - ab100659 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity < 70 pg/ml Range 0.069 ng/ml - 50 ng/ml

Human TREM-1 ELISA Kit - RAB0501 from Sigma-Aldrich Category ELISA Kit Prices $423.50 Sizes 1 kt

Human TREM1 ELISA Kit (Sandwich ELISA) - LS-F5220 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 6 pg/ml Range 68.6-16667 pg/ml

Mouse TREM1 ELISA Kit (Sandwich ELISA) - LS-F5995 from LifeSpan Bioscience Category ELISA Kit Prices $460.00 Sizes 1 plate Sensitivity 6.7 pg/ml Range 68.6-16667 pg/ml

Pig TREM1 ELISA Kit (Sandwich ELISA) - LS-F5996 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 12.4 pg/ml Range 68.6-16667 pg/ml

Human TREM1 ELISA Kit (Sandwich ELISA) - LS-F203 from LifeSpan Bioscience Category ELISA Kit Prices $460.00, $840.00, $1,960.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 68.6 pg/ml Range 68.6-16667 pg/ml

Human TREM1 ELISA Kit (Sandwich ELISA) - LS-F727 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 68.6-16667 pg/ml

Mouse TREM1 ELISA Kit (Sandwich ELISA) - LS-F298 from LifeSpan Bioscience Category ELISA Kit Prices $600.00, $1,100.00, $2,520.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 0.274 ng/ml Range 68.6-16667 pg/ml

Mouse TREM1 ELISA Kit (Sandwich ELISA) - LS-F2948 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 10 pg/ml Range 68.6-16667 pg/ml

Human TREM-1 DuoSet ELISA - DY1278B from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 93.80 - 6,000 pg/mL

Mouse TREM-1 DuoSet ELISA - DY1187 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 62.50 - 4,000 pg/mL

Mouse/Rat TREM-1 Quantikine ELISA Kit - MTRM10 from R&D Systems Category ELISA Kit Prices $479.00 Sizes 1 kit Sensitivity 5.4 pg/mL Range 31.3 - 2,000 pg/mL (Cell Culture Supernates, Tissue Homogenates, Serum, EDTA Plasma, Heparin Plasma)

Quantikine Immunoassay Control Set 867 Human TREM-1 - QC210 from R&D Systems Category ELISA Kit Prices $125.00 Sizes 1 each

Human TREM-1 Quantikine ELISA Kit - DTRM10C from R&D Systems Category ELISA Kit Prices $499.00 Sizes 1 kit Sensitivity 15.2 pg/mL Range 62.5 - 4,000 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma, Saliva)

TREM-1 ELISA Kit (Human) : 96 Wells (OKAG00259) - OKAG00259 from Aviva Systems Biology Category ELISA Kit Prices $390.00 Sizes 96 wells Sensitivity 94 pg/mL Range 94-6,000 pg/mL

Triggering Receptor Expressed on Myeloid Cells-1, TREM-1, Human, ELISA Kit - E-EL-H1597 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 37.5 Range 62.5-4000pg/mL

Triggering Receptor Expressed On Myeloid Cells 1 (TREM1), Human, ELISA Kit - SEA213Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 5.6pg/mL Range 15.6-1,000pg/mL

Triggering receptor expressed on myeloid cells 1, TREM1, Human, ELISA Kit - E0213h from ARP American Research Products Category ELISA Kit Prices $476.00 Sizes 96 t Range 0.156-10 ng/mL

Triggering Receptor Expresses on Myeloid Cells-1, TREM-1, Human, ELISA Kit - CSB-E04836h from ARP American Research Products Category ELISA Kit Prices $450.00, $595.00, $596.00, $599.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 7.8pg/ml Range 31.25pg/ml-2000pg/ml

Triggering Receptor Expresses on Myeloid Cells-1, TREM-1, Mouse, ELISA Kit - E-EL-M0645 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 4.688 Range 7.813-500pg/mL

Triggering Receptor Expresses on Myeloid Cells-1, TREM-1, Rat, ELISA Kit - E-EL-R1025 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 4.688 Range 7.813-500pg/mL

Triggering Receptor Expressed on Myeloid Cells-1, TREM-1, Rabbit, ELISA Kit - E-EL-RB0288 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Triggering Receptor Expressed on Myeloid Cells-1, TREM-1, Chicken, ELISA Kit - E-EL-Ch0789 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Triggering Receptor Expressed on Myeloid Cells-1, TREM-1, Porcine, ELISA Kit - E-EL-P2072 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

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