TREM1

Gene Symbol	TREM1
Entrez Gene	54210
Alt Symbol	CD354, TREM-1
Species	Human
Gene Type	protein-coding
Description	triggering receptor expressed on myeloid cells 1
Other Description	triggering receptor expressed on monocytes 1|triggering-receptor TREM1
Swissprots	B4DWG2 Q5T2C9 K7EJW1 Q9NP99 Q86YU1 Q53FL8
Accessions	ABB01010 CAJ78384 EAX04043 EAX04044 Q9NP99 AF196329 AAF71694 AF287008 AAF90197 AK130673 AK223264 BAD96984 AK292162 BAF84851 AK301519 BAG63024 AK313104 BAG35927 AY074783 AAL74018 BC017773 AAH17773 DA362458 DA938757 DQ892009 ABM82935 DQ895198 ABM86124 XM_006715117 XP_006715180 XM_011514696 XP_011512998 XM_011514697 XP_011512999 NM_001242589 NP_001229518 NM_001242590 NP_001229519 NM_018643 NP_061113
Function	Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock. {ECO:0000269|PubMed:10799849, ECO:0000269|PubMed:11323674}.
Subcellular Location	Isoform 1: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity	Highly expressed in adult liver, lung and spleen than in corresponding fetal tissue. Also expressed in the lymph node, placenta, spinal cord and heart tissues. Expression is more elevated in peripheral blood leukocytes than in the bone marrow and in normal cells than malignant cells. Expressed at low levels in the early development of the hematopoietic system and in the promonocytic stage and at high levels in mature monocytes. Strongly expressed in acute inflammatory lesions caused by bacteria and fungi. Isoform 2 was detected in the lung, liver and mature monocytes. {ECO:0000269|PubMed:10799849, ECO:0000269|PubMed:11922939}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TREM1 full length protein - ab132233 from Abcam Category Protein Source Wheat germ Species Human

Human TREM1 full length protein - ab151651 from Abcam Category Protein Source HEK 293 cells Species Human

Human TREM1 protein fragment - ab82984 from Abcam Category Protein Source E. coli Species Human

Human TREM1 protein fragment - ab82983 from Abcam Category Protein Source E. coli Species Human

TREM1 peptide - ab107110 from Abcam Category Peptide

TREM1 peptide - ab107111 from Abcam Category Peptide

TREM1 Antibody Blocking Peptide - LS-E6193 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TREM1 Antibody Blocking Peptide - LS-E31384 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

TREM1 Antibody Blocking Peptide - LS-E23170 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TREM-1 Recombinant Protein - H00054210-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human TREM-1 Protein - NBP2-22887 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

TREM-1 Recombinant Protein - H00054210-G01 from Novus Biologicals Category Protein Prices $579.00 Sizes 10 µg Species Human

TREM1-Antibody-C-term-Blocking-Peptide - BP18834b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human TREM-1 Fc Chimera, CF - 1278-TR-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

TREM1 Protein (OPPA01364) - OPPA01364 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

Human TREM 1 protein - orb84040 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

Human TREM1 protein - orb81430 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

Human TREM1 protein - orb49690 from Biorbyt Category Protein Prices $255.00, $349.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Human TREM 1 protein - orb83146 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

TREM1 protein (His tag) - 80R-2523 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

CD354 Blocking Peptide - abx161059 from Abbexa Category Peptide Species Human, Mouse, Rat

Human TREM1 Protein - abx069479 from Abbexa Category Protein Source E.coli Species Human

TREM1 (21-205, His-tag) - AR50595PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

TREM1 (21-205, His-tag) - AR50595PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

TREM1 - H00054210-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

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