H3F3C

Gene Symbol H3F3C
Entrez Gene 440093
Alt Symbol H3.5
Species Human
Gene Type protein-coding
Description H3 histone, family 3C
Other Description histone H3.3C|histone H3.5|histone variant H3.5
Swissprots E9P281 Q6NXT2
Accessions EAW88541 Q6NXT2 AI016942 BC066906 AAH66906 HQ873957 ADW85800 NM_001013699 NP_001013721
Function Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Hominid-specific H3.5/H3F3C preferentially colocalizes with euchromatin, and it is associated with actively transcribed genes. {ECO:0000269|PubMed:21274551}.
Subcellular Location Nucleus. Chromosome.
Tissue Specificity Specifically expressed in the seminiferous tubules of testis. {ECO:0000269|PubMed:21274551}.
Top Pathways Systemic lupus erythematosus, Alcoholism, Transcriptional misregulation in cancer

Human Histone H3.3C full length protein - ab166533 from Abcam

Category Protein
Source Wheat germ
Species Human
ab166533 on a 12.5% SDS-PAGE stained with Coomassie Blue.

H3F3C Recombinant Protein - H00440093-P01 from Novus Biologicals

Category Protein
Species Human

Me2-H3K9-Antibody-Blocking-peptide - BP1051b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Histone H3.3C - H00440093-P01 from Acris Antibodies

Category Protein
Prices $340.00
Sizes 2 µg
Species Human

Histone H3.3C - H00440093-P01-10 from Acris Antibodies

Category Protein
Prices $370.00
Sizes 10 µg
Species Human

Histone H3.3C - H00440093-P01-25 from Acris Antibodies

Category Protein
Prices $520.00
Sizes 25 µg
Species Human

Histone H3 citrulline R2 + R8 + R17 peptide - pep0208 from Covalab

Category Peptide
Species Human

Recombinant Human Histone H3.3C(H3F3C) - CSB-YP747371HU CSB-EP747371HU CSB-BP747371HU CSB-MP747371HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

H3F3C Peptide, Human - M34GP06816H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Histone H3.3C (H3F3C), Recombinant Protein - MBS1394414 from MyBioSource

Category Protein
Prices $870.00, $870.00, $1,095.00, $1,095.00, $1,270.00, $1,270.00, $1,725.00, $1,725.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

Histone H3.3C (H3F3C), Recombinant Protein - MBS1235195 from MyBioSource

Category Protein
Prices $875.00, $875.00, $1,100.00, $1,100.00, $1,275.00, $1,275.00, $1,730.00, $1,730.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
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