H3F3C

Gene Symbol H3F3C
Entrez Gene 440093
Alt Symbol H3.5
Species Human
Gene Type protein-coding
Description H3 histone, family 3C
Other Description histone H3.3C|histone H3.5|histone variant H3.5
Swissprots E9P281 Q6NXT2
Accessions EAW88541 Q6NXT2 AI016942 BC066906 AAH66906 HQ873957 ADW85800 NM_001013699 NP_001013721
Function Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Hominid-specific H3.5/H3F3C preferentially colocalizes with euchromatin, and it is associated with actively transcribed genes. {ECO:0000269|PubMed:21274551}.
Subcellular Location Nucleus. Chromosome.
Tissue Specificity Specifically expressed in the seminiferous tubules of testis. {ECO:0000269|PubMed:21274551}.
Top Pathways Systemic lupus erythematosus, Alcoholism, Transcriptional misregulation in cancer

Histone H3F3C CRISPR/Cas9 KO Plasmid (h) - sc-416021 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histone H3F3C HDR Plasmid (h) - sc-416021-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histone H3F3C Double Nickase Plasmid (h) - sc-416021-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histone H3F3C Double Nickase Plasmid (h2) - sc-416021-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histone H3F3C CRISPR Activation Plasmid (h) - sc-416021-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histone H3F3C CRISPR Activation Plasmid (h2) - sc-416021-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histone H3F3C Lentiviral Activation Particles (h) - sc-416021-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histone H3F3C Lentiviral Activation Particles (h2) - sc-416021-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Histone H3F3C siRNA (h) - sc-105721 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Histone H3F3C shRNA Plasmid (h) - sc-105721-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Histone H3F3C shRNA (h) Lentiviral Particles - sc-105721-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN9850 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9850 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04505 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04505

H3F3C siRNA (Human) - CRJ8235 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

H3F3C RNAi - H00440093-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

H3F3C - MBS8217397 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human H3F3C (NM_001013699.2) - SHH310021 from Creative biogene

Category siRNA
Species Reactivities Human

Human H3F3C siRNA - orb278736 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

H3F3C shRNA Plasmid (Human) - CHJ8235 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

H3F3C miRNA 3'UTR clone - MiUTR3H-15069 from Creative biogene

Species Reactivities Human
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