| Gene Symbol |
MMP15
|
| Entrez Gene |
4324
|
| Alt Symbol |
MT2-MMP, MTMMP2, SMCP-2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
matrix metallopeptidase 15 (membrane-inserted)
|
| Other Description |
MMP-15|MT-MMP 2|MT2MMP|matrix metalloproteinase 15 (membrane-inserted)|matrix metalloproteinase-15|membrane-type matrix metalloproteinase 2|membrane-type-2 matrix metalloproteinase
|
| Swissprots |
P51511 Q14111 A0A2U6
|
| Accessions |
ABJ53423 EAW82965 EAW82966 P51511 AW161057 BC006412 BC036495 AAH36495 BC055428 AAH55428 BF507560 BT006715 AAP35361 D85510 BAA22225 D86331 BAA13071 Z48482 CAA88373 NM_002428 NP_002419
|
| Function |
Endopeptidase that degrades various components of the extracellular matrix. May activate progelatinase A. {ECO:0000269|PubMed:9461298}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}; Extracellular side {ECO:0000305}.
|
| Tissue Specificity |
Appeared to be synthesized preferentially in liver, placenta, testis, colon and intestine. Substantial amounts are also detected in pancreas, kidney, lung, heart and skeletal muscle.
|
![Western Blot: MMP15 Overexpression Lysate (Adult Normal) [NBL1-13154] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for MMP15.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/3541_MMP15%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-13154-img0002.jpg)