MMP15

Gene Symbol MMP15
Entrez Gene 4324
Alt Symbol MT2-MMP, MTMMP2, SMCP-2
Species Human
Gene Type protein-coding
Description matrix metallopeptidase 15 (membrane-inserted)
Other Description MMP-15|MT-MMP 2|MT2MMP|matrix metalloproteinase 15 (membrane-inserted)|matrix metalloproteinase-15|membrane-type matrix metalloproteinase 2|membrane-type-2 matrix metalloproteinase
Swissprots P51511 Q14111 A0A2U6
Accessions ABJ53423 EAW82965 EAW82966 P51511 AW161057 BC006412 BC036495 AAH36495 BC055428 AAH55428 BF507560 BT006715 AAP35361 D85510 BAA22225 D86331 BAA13071 Z48482 CAA88373 NM_002428 NP_002419
Function Endopeptidase that degrades various components of the extracellular matrix. May activate progelatinase A. {ECO:0000269|PubMed:9461298}.
Subcellular Location Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}; Extracellular side {ECO:0000305}.
Tissue Specificity Appeared to be synthesized preferentially in liver, placenta, testis, colon and intestine. Substantial amounts are also detected in pancreas, kidney, lung, heart and skeletal muscle.

MT-MMP-2 (C-20) - sc-8844 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MT-MMP-2 (N-19) - sc-8843 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MT-MMP-2 (YZ-12) - sc-80213 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
MT-MMP-2 (YZ-12): sc-80213. Western blot analysis of MT-MMP-2 expression in non-transfected 293T: sc-117752 (A), mouse MT-MMP-2 transfected 293T: sc-121817 (B) and HeLa (C) whole cell lysates.

MT-MMP-2 (MM0028-5D11) - sc-101452 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-MMP15 antibody - ab15475 from Abcam

Prices $370.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab15475 stained Jeg3 cells. The cells were 100% methanol fixed (5 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab15475, 5g/ml) overnight at +4°C. The secondary antibody (green) was ab96899, Dylight® 488 goat anti-rabbit IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM

Anti-MMP15 antibody - ab53770 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MMP15 antibody (ab53770) at 1/500 dilutionLane 1 : Extracts from MDA-MB-435 cellsLane 2 : Extracts from MDA-MB-435 cells, plus peptide

Anti-MMP15 antibody - ab72688 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MMP15 antibody (ab72688) at 1/500 dilutionLane 1 : COS7 cell extract treated with etoposide (25uM, 1 hour)Lane 2 : COS7 cell extract treated with etoposide (25uM, 1 hour) with immunising peptide at 5 µgLysates/proteins at 5 µg per lane.

Anti-MMP15 antibody - ab39693 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MMP15 antibody (ab39693) at 1/1000 dilutionLane 1 : SF treated SW 620 LysateLane 2 : TPA treated SW 620 LysateLane 3 : IL1-alpha treated SW 620 LysateLane 4 : IL1-beta treated SW 620 LysateLane 5 : TNF-alpha treated SW 620 LysateLysates/proteins at 10 µl per lane.

Anti-MMP15 antibody - ab28200 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MMP15 antibody - ab39025 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MMP15 antibody [MM0028-5D11] - ab56308 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0028-5D11
ab56308 at 1/200 dilution, staining MMP15 in human placental tissue section by Immunohistochemistry (Formalin/PFA fixed paraffin-embedded sections).

Anti-MMP15 antibody, prediluted - ab15476 from Abcam

Prices $370.00
Sizes 7 ml
Host Rabbit
Clonality Polyclonal
ab15476 staining MMP15 in human placenta by Immunocytochemistry (FFPE-sections).

Anti-MMP15 antibody - N-terminal - ab135562 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MMP15 antibody - N-terminal (ab135562) at 1/100 dilutionLane 1 : Mouse brain tissue lysateLane 2 : HL60 cells lysateLysates/proteins at 12.5 µg per lane.

Anti-MMP15 Antibody (aa180-194) - LS-C3111 from LifeSpan Bioscience

Prices $285.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MMP15 Antibody (aa281-294) - LS-C16428 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-MMP15 Antibody (C-Terminus) - LS-C95920 from LifeSpan Bioscience

Prices $415.00, $690.00
Sizes 500 µl, 1 ml
Host Rabbit
Clonality Polyclonal

Anti-MMP15 Antibody - LS-C72228 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MMP15 Antibody - LS-C72229 from LifeSpan Bioscience

Prices $575.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal

Anti-MMP15 Antibody - LS-C124068 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MMP15 Antibody - LS-C50677 from LifeSpan Bioscience

Prices $440.00
Sizes 250 µl
Host Rabbit
Clonality Polyclonal
Human placenta stained with Anti-MMP-15 antibody

Anti-MMP15 Antibody - LS-C124069 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MMP15 Antibody (aa113-162) - LS-C121089 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from COS7 cells, treated with etoposide 25 uM 1h, using MMP15 (Cleaved-Tyr132) Antibody. The lane on the right is treated with the synthesized peptide.

Anti-MMP15 Antibody - LS-C189090 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-MMP15 Antibody - LS-C189320 from LifeSpan Bioscience

Prices $485.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal

Anti-MMP15 Antibody (aa168-196, AP) - LS-C263277 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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