Gene Symbol | SPACA3 |
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Entrez Gene | 124912 |
Alt Symbol | 1700025M08Rik, ALLP17, CT54, LYC3, LYZL3, SLLP1 |
Species | Human |
Gene Type | protein-coding |
Description | sperm acrosome associated 3 |
Other Description | cancer/testis antigen 54|lysozyme-like acrosomal sperm-specific secretory protein ALLP-17|lysozyme-like protein 3|lysozyme-like sperm-specific secretory protein ALLP17|sperm acrosome membrane-associated protein 3|sperm lysozyme like protein 1|sperm lysozyme-like protein 1|sperm lyzozyme-like acrosomal protein 1|sperm protein reactive with ASA|sperm protein reactive with antisperm antibodies |
Swissprots | Q8IXA5 Q7Z4Y5 |
Accessions | AAP97222 EAW80217 EAW80218 Q8IXA5 AF216311 AAK01478 AY358653 AAQ89016 BC029867 AAH29867 BC100886 AAI00887 BC100887 AAI00888 NM_173847 NP_776246 |
Function | Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro. {ECO:0000269|PubMed:12606493}. |
Subcellular Location | Isoform 1: Cytoplasmic vesicle, secretory vesicle, acrosome membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. Note=Anterior acrosome in non- capacitated spermatozoa and retained in the equatorial segment and in the luminal face of both the inner and outer acrosomal membranes following capacitation and the acrosome reaction. {ECO:0000250}. |
Tissue Specificity | The processed form is expressed in sperm (at protein level). Expressed in testis, epididymis and placenta. {ECO:0000269|PubMed:12606493, ECO:0000269|PubMed:16014814}. |
SPACA3 (C-13) - sc-160820 from Santa Cruz Biotechnology
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SPACA3 (S-14) - sc-160824 from Santa Cruz Biotechnology
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Anti-SPACA3 antibody - ab121768 from Abcam
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Anti-SPACA3 antibody - C-terminal - ab178725 from Abcam
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Anti-SPACA3 Antibody (C-Terminus) - LS-C186804 from LifeSpan Bioscience
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SPACA3 Antibody - NBP1-89136 from Novus Biologicals
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Anti-SPACA3 antibody produced in rabbit - HPA023633 from Sigma-Aldrich
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SPACA3 antibody - 70R-20469 from Fitzgerald
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SPACA3 / LYC3 antibody - 21137-1-AP from Acris Antibodies
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SPACA3 antibody - 21137-1-AP from Proteintech Group
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Anti-SPACA3 (aa 138-215) polyclonal antibody - DPABH-20086 from Creative Diagnostics
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Anti-SPACA3 monoclonal antibody - DCABH-201514 from Creative Diagnostics
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sperm acrosome associated 3 , Polyclonal Antibody - MBS716520 from MyBioSource
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SPACA3 Antibody - H00124912-B01 from Novus Biologicals
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SPACA3, Polyclonal Antibody - MBS5301278 from MyBioSource
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SPACA3 Antibody - abx122919 from Abbexa
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SPACA3 Antibody - 42941 from Signalway Antibody
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SPACA3 Antibody - SPACA3-301AP from FabGennix
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SPACA3 Antibody - SPACA3-321AP from FabGennix
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SPACA3 Antibody - SPACA3-331AP from FabGennix
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SPACA3 Antibody - SPACA3-312AP from FabGennix
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SPACA3 antibody - orb360222 from Biorbyt
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Recombinant Anti-Human SPACA3 Antibody - MOB-1351z from Creative Biolabs
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Recombinant Anti-Human SPACA3 Antibody scFv Fragment - MOB-1351z-S(P) from Creative Biolabs
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Recombinant Anti-Human SPACA3 Antibody Fab Fragment - MOB-1351z-F(E) from Creative Biolabs
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