Gene Symbol | SPACA3 |
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Entrez Gene | 124912 |
Alt Symbol | 1700025M08Rik, ALLP17, CT54, LYC3, LYZL3, SLLP1 |
Species | Human |
Gene Type | protein-coding |
Description | sperm acrosome associated 3 |
Other Description | cancer/testis antigen 54|lysozyme-like acrosomal sperm-specific secretory protein ALLP-17|lysozyme-like protein 3|lysozyme-like sperm-specific secretory protein ALLP17|sperm acrosome membrane-associated protein 3|sperm lysozyme like protein 1|sperm lysozyme-like protein 1|sperm lyzozyme-like acrosomal protein 1|sperm protein reactive with ASA|sperm protein reactive with antisperm antibodies |
Swissprots | Q8IXA5 Q7Z4Y5 |
Accessions | AAP97222 EAW80217 EAW80218 Q8IXA5 AF216311 AAK01478 AY358653 AAQ89016 BC029867 AAH29867 BC100886 AAI00887 BC100887 AAI00888 NM_173847 NP_776246 |
Function | Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro. {ECO:0000269|PubMed:12606493}. |
Subcellular Location | Isoform 1: Cytoplasmic vesicle, secretory vesicle, acrosome membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. Note=Anterior acrosome in non- capacitated spermatozoa and retained in the equatorial segment and in the luminal face of both the inner and outer acrosomal membranes following capacitation and the acrosome reaction. {ECO:0000250}. |
Tissue Specificity | The processed form is expressed in sperm (at protein level). Expressed in testis, epididymis and placenta. {ECO:0000269|PubMed:12606493, ECO:0000269|PubMed:16014814}. |
Human SPACA3 full length protein - ab165225 from Abcam
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SPACA3 Antibody Blocking Peptide - LS-E24139 from LifeSpan Bioscience
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Recombinant Human SPACA3 Protein - H00124912-P01 from Novus Biologicals
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SPACA3 / LYC3 - H00124912-P01-10 from Acris Antibodies
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SPACA3 / LYC3 - H00124912-P01-25 from Acris Antibodies
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SPACA3 fusion protein - Ag15589 from Proteintech Group
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SPACA3 fusion protein - Ag15761 from Proteintech Group
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Recombinant Human SPACA3, GST-tagged - SPACA3-2891H from Creative Biomart
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Recombinant Human Sperm acrosome membrane-associated protein 3(SPACA3) - CSB-YP812887HU CSB-EP812887HU CSB-BP812887HU CSB-MP812887HU from Cusabio
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SPACA3 / LYC3 - TP315959 from Acris Antibodies
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Recombinant Human SPACA3 protein, GST-tagged - SPACA3-526H from Creative Biomart
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Recombinant Human SPACA3 protein, MYC/DDK-tagged - SPACA3-527H from Creative Biomart
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SPACA3 Recombinant Protein Antigen - NBP1-89136PEP from Novus Biologicals
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SACA3-Antibody-N-term-Blocking-peptide - BP5502a from Abgent, a WuXi AppTec company
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SPACA3 Peptide, Human - M34GP14941H from Creative Peptides
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Sperm acrosome membrane-associated protein 3 (SPACA3), Recombinant Protein - MBS1356932 from MyBioSource
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