Gene Symbol | RAD18 |
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Entrez Gene | 56852 |
Alt Symbol | RNF73 |
Species | Human |
Gene Type | protein-coding |
Description | RAD18 E3 ubiquitin protein ligase |
Other Description | E3 ubiquitin-protein ligase RAD18|RAD18 homolog|RAD18, S. cerevisiae, homolog|RING finger protein 73|hHR18|hRAD18|postreplication repair protein RAD18|postreplication repair protein hRAD18p |
Swissprots | Q9NRT6 Q58F55 Q9NS91 |
Accessions | AAX44049 EAW63948 EAW63949 Q9NS91 AB035274 BAA99284 AF169796 AAF80856 AK023075 BAB14392 AK123966 AK222771 BAD96491 AY004333 AAF86618 BC001302 AAH01302 DQ891197 ABM82123 DQ894380 ABM85306 DW433240 NM_020165 NP_064550 |
Function | E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap- filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono- ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity. {ECO:0000269|PubMed:17108083, ECO:0000269|PubMed:21659603}. |
Subcellular Location | Nucleus {ECO:0000250}. |
Human RAD18 full length protein - ab112417 from Abcam
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Human RAD18 protein fragment - ab112418 from Abcam
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RAD18 Antibody Blocking Peptide - LS-E15923 from LifeSpan Bioscience
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RAD18 Antibody Blocking Peptide - LS-E15922 from LifeSpan Bioscience
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Recombinant Human RAD18 Protein - H00056852-Q01 from Novus Biologicals
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Recombinant Human RAD18 Protein - H00056852-P01 from Novus Biologicals
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Human RAD18 protein - orb244987 from Biorbyt
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RAD18 Blocking Peptide - 33R-5416 from Fitzgerald
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RAD18 Blocking Peptide - 33R-4617 from Fitzgerald
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RAD18 Blocking Peptide - abx063917 from Abbexa
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RAD18 / RNF73 - H00056852-P01-10 from Acris Antibodies
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RAD18 / RNF73 - H00056852-P01-25 from Acris Antibodies
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RAD18 / RNF73 - H00056852-Q01-10 from Acris Antibodies
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RAD18 / RNF73 - H00056852-Q01-25 from Acris Antibodies
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RAD18 fusion protein - ag12954 from Proteintech Group
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RAD18 fusion protein - Ag12944 from Proteintech Group
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Recombinant Human RAD18 - RAD18-29578TH from Creative Biomart
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Recombinant Human RAD18 - RAD18-29579TH from Creative Biomart
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RAD18 Blocking Peptide - CBP2723 from Cohesion Biosciences
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Recombinant Human E3 ubiquitin-protein ligase RAD18(RAD18) - CSB-YP889102HU CSB-BP889102HU CSB-MP889102HU from Cusabio
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Recombinant human E3 ubiquitin-protein ligase RAD18 - CSB-EP889102HU from Cusabio
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RAD18 / RNF73 - TP301700 from Acris Antibodies
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RAD18 Recombinant Protein Antigen - NBP2-33865PEP from Novus Biologicals
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RAD18 Protein - NBP2-33851PEP from Novus Biologicals
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RAD18 Peptide, Human - M34GP12905H from Creative Peptides
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