TRPC3

Gene Symbol TRPC3
Entrez Gene 7222
Alt Symbol TRP3
Species Human
Gene Type protein-coding
Description transient receptor potential cation channel, subfamily C, member 3
Other Description hTrp-3|short transient receptor potential channel 3|transient receptor potential cation channel subfamily C member 3 variant c|transient receptor protein 3
Swissprots O00593 E9PCJ9 Q13507 A7VJS1 Q52M35 Q15660 Q5G1L5
Accessions AAY40971 CAJ01297 EAX05243 Q13507 AB255423 BAF76423 AB255424 BAF76424 AY865574 AAW62292 BC093682 AAH93682 BC093684 AAH93684 BC143239 KC207570 AGG20159 X89068 CAA61448 Y13758 CAA74083 XM_011532217 XP_011530519 XM_011532218 XP_011530520 XM_011532219 XP_011530521 NM_001130698 NP_001124170 NM_003305 NP_003296
Function Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol 1,4,5- triphosphate receptors (ITPR) with bound IP3. May also be activated by internal calcium store depletion. {ECO:0000269|PubMed:20095964, ECO:0000269|PubMed:8646775, ECO:0000269|PubMed:9417057, ECO:0000269|PubMed:9930701}.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Expressed predominantly in brain and at much lower levels in ovary, colon, small intestine, lung, prostate, placenta and testis.

TRPC3/6/7 CRISPR/Cas9 KO Plasmid (h) - sc-403740 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRPC3/6/7 HDR Plasmid (h) - sc-403740-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRPC3/6/7 Double Nickase Plasmid (h) - sc-403740-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRPC3/6/7 Double Nickase Plasmid (h2) - sc-403740-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRPC3/6/7 CRISPR Activation Plasmid (h) - sc-403740-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRPC3/6/7 CRISPR Activation Plasmid (h2) - sc-403740-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRPC3/6/7 Lentiviral Activation Particles (h) - sc-403740-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRPC3/6/7 Lentiviral Activation Particles (h2) - sc-403740-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRPC3 siRNA (h) - sc-42666 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TRPC3 shRNA Plasmid (h) - sc-42666-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TRPC3 shRNA (h) Lentiviral Particles - sc-42666-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TRPC3 RNAi - H00007222-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU031761 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22054 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22054 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03880 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03880

TRPC3 siRNA (Human) - CRH4946 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TRPC3 - MBS8215508 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TRPC3 (NM_003305.2) - SHH435548 from Creative biogene

Category siRNA
Species Reactivities Human

Human TRPC3 siRNA - orb265448 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TRPC3 shRNA Plasmid (Human) - CHH4946 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TRPC3 miRNA 3'UTR clone - MiUTR1H-10781 from Creative biogene

Species Reactivities Human

TRPC3 miRNA 3'UTR clone - MiUTR3H-04897 from Creative biogene

Species Reactivities Human
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