AFF4

Gene Symbol AFF4
Entrez Gene 27125
Alt Symbol AF5Q31, MCEF
Species Human
Gene Type protein-coding
Description AF4/FMR2 family, member 4
Other Description AF4/FMR2 family member 4|ALL1-fused gene from chromosome 5q31 protein|major CDK9 elongation factor-associated protein
Swissprots Q59FB3 Q9UHB7 B2RP19 B7WPD2 Q6P592 Q8TDR1 Q498B2 Q9P0E4
Accessions EAW62301 EAW62302 EAW62303 EAW62304 EAW62305 Q9UHB7 AA706988 AB209547 BAD92784 AF161355 AAF28915 AF173886 AAQ13633 AF197927 AAF18981 AF213987 AAM00184 AK024831 AK055638 AK126818 AK307407 BC025700 AAH25700 BC040454 BC063007 AAH63007 BC100287 AAI00288 BC137226 AAI37227 BC144538 BX537585 DA934874 XM_005271963 XP_005272020 XM_005271964 XP_005272021 XM_006714587 XP_006714650 NM_014423 NP_055238
Function Key component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. In the SEC complex, AFF4 acts as a central scaffold that recruits other factors through direct interactions with ELL proteins (ELL, ELL2 or ELL3) and the P-TEFb complex. In case of infection by HIV-1 virus, the SEC complex is recruited by the viral Tat protein to stimulate viral gene expression. {ECO:0000269|PubMed:20159561, ECO:0000269|PubMed:20471948, ECO:0000269|PubMed:23251033}.
Subcellular Location Nucleus {ECO:0000269|PubMed:12065898}. Note=Associates to transcriptionally active chromatin but not at snRNA genes. {ECO:0000250}.
Tissue Specificity Ubiquitously expressed. Strongly expressed in heart, placenta, skeletal muscle, pancreas and to a lower extent in brain. {ECO:0000269|PubMed:10588740, ECO:0000269|PubMed:12065898}.

AF4/FMR2 family member 4 (AFF4), Human, ELISA Kit - E01A1303 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

AFF4 (Human) Matched Antibody Pair - H00027125-AP21 from Acris Antibodies

Category Antibody Pair
Prices $610.00
Sizes 1 set

AF4/FMR2 family member 4 (AFF4), ELISA Kit - MBS7213839 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

AF4/FMR2 family member 4 (AFF4), ELISA Kit - MBS7218254 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

AF4/FMR2 family member 4 (AFF4), ELISA Kit - MBS7223663 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

AF4/FMR2 family member 4 (AFF4), ELISA Kit - MBS7203195 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

AF4/FMR2 family member 4 (AFF4), ELISA Kit - MBS7204489 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

AF4/FMR2 family member 4 (AFF4), ELISA Kit - MBS7208855 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

AF4/FMR2 family member 4 (AFF4), ELISA Kit - MBS7211673 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

AF4/FMR2 family member 4 (AFF4), ELISA Kit - MBS7203770 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

AF4/FMR2 family member 4 (AFF4), ELISA Kit - MBS7224258 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

AF4/FMR2 family member 4 (AFF4), ELISA Kit - MBS7226073 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

AF4/FMR2 family member 4 (AFF4), ELISA Kit - MBS7219951 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

AF4/FMR2 family member 4 (AFF4), ELISA Kit - MBS7204854 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human AFF4 ELISA Kit - E001128 from Biobool

Category ELISA Kit

anti-AFF4 antibody - ARG57330 from Arigo Biolaboratories

Category ELISA Kit
Search more