Gene Symbol | CALCRL |
---|---|
Entrez Gene | 10203 |
Alt Symbol | CGRPR, CRLR |
Species | Human |
Gene Type | protein-coding |
Description | calcitonin receptor-like |
Other Description | CGRP type 1 receptor|calcitonin gene-related peptide type 1 receptor|calcitonin receptor-like receptor |
Swissprots | A8K6G5 Q53TS5 Q16602 Q53S02 A8KAD3 |
Accessions | AAY14806 AAY14996 EAX10925 EAX10926 Q16602 AA436933 AA961493 AK291630 BAF84319 AK292998 BAF85687 AL602685 AY389506 AAQ91332 BC156827 AAI56828 BQ002778 CB270158 DA097876 DA215003 DA217003 DA883991 DQ280490 DQ280491 ABC16643 L76380 AAC41994 U17473 AAA62158 XM_005246231 XP_005246288 XM_005246232 XP_005246289 XM_005246234 XP_005246291 NM_001271751 NP_001258680 NM_005795 NP_005786 |
Function | Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3 (By similarity). Receptor for adrenomedullin together with RAMP2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. {ECO:0000250, ECO:0000269|PubMed:22102369}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Predominantly expressed in the lung and heart. |
Top Pathways | Vascular smooth muscle contraction, Neuroactive ligand-receptor interaction |
CRLR (V-20) - sc-18007 from Santa Cruz Biotechnology
|
||||||||
CRLR (H-42) - sc-30028 from Santa Cruz Biotechnology
|
||||||||
CRLR (P-19) - sc-31569 from Santa Cruz Biotechnology
|
||||||||
CRLR (N-18) - sc-31568 from Santa Cruz Biotechnology
|
||||||||
Anti-CRLR antibody - ab84467 from Abcam
|
||||||||
Anti-CRLR antibody - ab173562 from Abcam
|
||||||||
Anti-CALCRL / CGRP Receptor Antibody (Cytoplasmic Domain) IHC-plus⢠- LS-A6731 from LifeSpan Bioscience
|
||||||||
Anti-CALCRL / CGRP Receptor Antibody (N-Terminus) IHC-plus⢠- LS-A6755 from LifeSpan Bioscience
|
||||||||
Anti-CALCRL / CGRP Receptor Antibody (C-Terminus) - LS-C12349 from LifeSpan Bioscience
|
||||||||
Anti-CALCRL / CGRP Receptor Antibody (C-Terminus) - LS-C12352 from LifeSpan Bioscience
|
||||||||
Anti-CALCRL / CGRP Receptor Antibody (aa436-461, Biotin) - LS-C183768 from LifeSpan Bioscience
|
||||||||
Anti-CALCRL / CGRP Receptor Antibody (aa436-461) - LS-C190563 from LifeSpan Bioscience
|
||||||||
Anti-CALCRL / CGRP Receptor Antibody (aa436-461, CF) - LS-C183769 from LifeSpan Bioscience
|
||||||||
Anti-CALCRL / CGRP Receptor Antibody (aa339-367, APC) - LS-C253305 from LifeSpan Bioscience
|
||||||||
Anti-CALCRL / CGRP Receptor Antibody (aa339-367, AP) - LS-C253306 from LifeSpan Bioscience
|
||||||||
Anti-CALCRL / CGRP Receptor Antibody (aa339-367, Azide-free, HRP) - LS-C253310 from LifeSpan Bioscience
|
||||||||
Anti-CALCRL / CGRP Receptor Antibody (aa339-367, FITC) - LS-C253308 from LifeSpan Bioscience
|
||||||||
Anti-CALCRL / CGRP Receptor Antibody (aa339-367) - LS-C329303 from LifeSpan Bioscience
|
||||||||
Anti-CALCRL / CGRP Receptor Antibody (aa339-367, PE) - LS-C253312 from LifeSpan Bioscience
|
||||||||
Anti-CALCRL / CGRP Receptor Antibody (aa108-157) - LS-C101953 from LifeSpan Bioscience
|
||||||||
Anti-CALCRL / CGRP Receptor Antibody (aa340-367) - LS-C159260 from LifeSpan Bioscience
|
||||||||
CALCRL Antibody - NBP1-59073 from Novus Biologicals
|
||||||||
CALCRL Antibody - NBP1-85643 from Novus Biologicals
|
||||||||
CALCRL Antibody - NLS6755 from Novus Biologicals
|
||||||||
CALCRL Antibody - NLS6731 from Novus Biologicals
|