DBF4B

Gene Symbol	DBF4B
Entrez Gene	80174
Alt Symbol	ASKL1, CHIFB, DRF1, ZDBF1B
Species	Human
Gene Type	protein-coding
Description	DBF4 zinc finger B
Other Description	ASK-like protein 1|DBF4 homolog B|Dbf4-related factor 1|activator of S-phase kinase-like protein 1|chiffon homolog B|protein DBF4 homolog B|zinc finger, DBF-type containing 1B
Swissprots	Q96B19 Q9H912 Q8NFT6 Q8TEX0 D3DX56
Accessions	EAW51581 EAW51582 EAW51583 EAW51584 EAW51585 EAW51586 EAW51587 Q8NFT6 AF448801 AAM73808 AF465820 AAL75985 AK023149 BAB14431 AK125771 BAG54245 AK295296 BAG58278 AK303282 BAG64361 AW290902 AY358101 AAQ88468 BC016158 AAH16158 BC026999 BC033660 BM476186 DA475446 XM_006722098 XP_006722161 XM_006722099 XP_006722162 XM_006722100 XP_006722163 XM_006722101 XP_006722164 XM_006722102 XP_006722165 XM_006722104 XP_006722167 XM_006722105 XP_006722168 XM_006722106 XP_006722169 XM_011525277 XP_011523579 XM_011525278 XP_011523580 XM_011525279 XP_011523581 XM_011525280 XP_011523582 XM_011525281 XP_011523583 XM_011525282 XP_011523584 XM_011525283 XP_011523585 XM_011525284 XP_011523586 NM_025104 NP_079380 NM_145663 NP_663696 NR_036623
Function	Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S and M phases. The complex CDC7-DBF4B selectively phosphorylates MCM2 subunit at 'Ser-40' and then is involved in regulating the initiation of DNA replication during cell cycle. {ECO:0000269|PubMed:12065429, ECO:0000269|PubMed:15668232, ECO:0000269|PubMed:17062569}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:12065429, ECO:0000269|PubMed:15668232}. Note=Predominantly found in soluble fraction but not in the chromatin-bound fraction.
Tissue Specificity	Widely expressed. Highly expressed in testis. {ECO:0000269|PubMed:12065429}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DBF4B full length protein - ab164212 from Abcam Category Protein Source Wheat germ Species Human

Human DBF4B full length protein - ab174933 from Abcam Category Protein Source Wheat germ Species Human

Human DBF4B protein fragment - ab164213 from Abcam Category Protein Source Wheat germ Species Human

Human DBF4B protein fragment - ab174934 from Abcam Category Protein Source Wheat germ Species Human

DBF4B / DRF1 Antibody Blocking Peptide - LS-E27672 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DBF4B / DRF1 Antibody Blocking Peptide - LS-E24942 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DBF4B / DRF1 Antibody Blocking Peptide - LS-E24941 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human DBF4B Protein - H00080174-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human DBF4B Protein - H00080174-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

DBF4B blocking peptide - GTX88106-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

DBF4B Peptide - AC21-2490-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

DBF4B / ASKL1 - H00080174-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

DBF4B / ASKL1 - H00080174-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

DBF4B / ASKL1 - H00080174-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

DBF4B / ASKL1 - H00080174-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

DBF4B Peptide - 42-344P from ProSci Category Peptide

Recombinant Human Protein DBF4 homolog B(DBF4B) - CSB-YP822784HU CSB-EP822784HU CSB-BP822784HU CSB-MP822784HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

DBF4B / ASKL1 (transcript variant 1) - TP314891 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

DBF4B, Peptide - MBS427534 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

DBF4B Protein - NBP2-13900PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

DBF4B-Antibody-Center-Blocking-Peptide - BP4825c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DBF4B Peptide, Human - M34GP04042H from Creative Peptides Category Peptide Source Synthetic. Species Human

Protein DBF4 homolog B (DBF4B), Recombinant Protein - MBS1487895 from MyBioSource Category Protein Prices $1,410.00, $1,410.00, $1,640.00, $1,640.00, $2,380.00, $2,380.00, $2,825.00, $2,825.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

DBF4B fusion protein - Ag23889 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

Recombinant Human DBF4B Protein, GST-tagged - DBF4B-2657H from Creative Biomart Category Protein Source Wheat Germ Species Human

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