DBF4B

Gene Symbol DBF4B
Entrez Gene 80174
Alt Symbol ASKL1, CHIFB, DRF1, ZDBF1B
Species Human
Gene Type protein-coding
Description DBF4 zinc finger B
Other Description ASK-like protein 1|DBF4 homolog B|Dbf4-related factor 1|activator of S-phase kinase-like protein 1|chiffon homolog B|protein DBF4 homolog B|zinc finger, DBF-type containing 1B
Swissprots Q96B19 Q9H912 Q8NFT6 Q8TEX0 D3DX56
Accessions EAW51581 EAW51582 EAW51583 EAW51584 EAW51585 EAW51586 EAW51587 Q8NFT6 AF448801 AAM73808 AF465820 AAL75985 AK023149 BAB14431 AK125771 BAG54245 AK295296 BAG58278 AK303282 BAG64361 AW290902 AY358101 AAQ88468 BC016158 AAH16158 BC026999 BC033660 BM476186 DA475446 XM_006722098 XP_006722161 XM_006722099 XP_006722162 XM_006722100 XP_006722163 XM_006722101 XP_006722164 XM_006722102 XP_006722165 XM_006722104 XP_006722167 XM_006722105 XP_006722168 XM_006722106 XP_006722169 XM_011525277 XP_011523579 XM_011525278 XP_011523580 XM_011525279 XP_011523581 XM_011525280 XP_011523582 XM_011525281 XP_011523583 XM_011525282 XP_011523584 XM_011525283 XP_011523585 XM_011525284 XP_011523586 NM_025104 NP_079380 NM_145663 NP_663696 NR_036623
Function Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S and M phases. The complex CDC7-DBF4B selectively phosphorylates MCM2 subunit at 'Ser-40' and then is involved in regulating the initiation of DNA replication during cell cycle. {ECO:0000269|PubMed:12065429, ECO:0000269|PubMed:15668232, ECO:0000269|PubMed:17062569}.
Subcellular Location Nucleus {ECO:0000269|PubMed:12065429, ECO:0000269|PubMed:15668232}. Note=Predominantly found in soluble fraction but not in the chromatin-bound fraction.
Tissue Specificity Widely expressed. Highly expressed in testis. {ECO:0000269|PubMed:12065429}.

Dbf4b CRISPR/Cas9 KO Plasmid (h) - sc-406464 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dbf4b HDR Plasmid (h) - sc-406464-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dbf4b Double Nickase Plasmid (h) - sc-406464-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dbf4b Double Nickase Plasmid (h2) - sc-406464-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dbf4b CRISPR Activation Plasmid (h) - sc-406464-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dbf4b CRISPR Activation Plasmid (h2) - sc-406464-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dbf4b Lentiviral Activation Particles (h) - sc-406464-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dbf4b Lentiviral Activation Particles (h2) - sc-406464-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dbf4b siRNA (h) - sc-93916 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dbf4b shRNA Plasmid (h) - sc-93916-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dbf4b shRNA (h) Lentiviral Particles - sc-93916-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DBF4B RNAi - H00080174-R06 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU096851 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® esiRNA - EHU102791 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6944 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6944 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR12768 from Sigma-Aldrich

Category miRNA

DBF4B siRNA (Human) - CRJ2784 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DBF4B RNAi - H00080174-R05 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

DBF4B - MBS8238660 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DBF4B (NM_025104.3) - SHH274709 from Creative biogene

Category siRNA
Species Reactivities Human

Human DBF4B siRNA - orb273285 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DBF4B shRNA Plasmid (Human) - CHJ2784 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DBF4B miRNA 3'UTR clone - MiUTR4H-TG02571 from Creative biogene

Species Reactivities Human
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