ZNF281

Gene Symbol ZNF281
Entrez Gene 23528
Alt Symbol ZBP-99, ZNP-99
Species Human
Gene Type protein-coding
Description zinc finger protein 281
Other Description GC-box-binding zinc finger protein 1|ZNP-99 transcription factor|transcription factor ZBP-99|zinc finger DNA-binding protein 99
Swissprots Q5RKW5 Q9Y2X9 Q9NY92 A6NF48 B3KMX2
Accessions CAH05622 EAW91313 Q9Y2X9 AF086540 AF125158 AAD21084 AJ132591 CAB70967 AJ132592 CAB70968 AK021707 AK022916 BAG51134 AK022921 BAG51136 AK027284 BAG51299 AK094701 AK297233 BAG59716 BC016000 BC051905 AAH51905 BC060820 AAH60820 BG611294 BP216938 BQ012001 BQ013454 DB150929 NM_001281293 NP_001268222 NM_001281294 NP_001268223 NM_012482 NP_036614
Function Transcription repressor that plays a role in regulation of embryonic stem cells (ESCs) differentiation. Required for ESCs differentiation and acts by mediating autorepression of NANOG in ESCs: binds to the NANOG promoter and promotes association of NANOG protein to its own promoter and recruits the NuRD complex, which deacetylates histones. Not required for establishement and maintenance of ESCs (By similarity). Represses the transcription of a number of genes including GAST, ODC1 and VIM. Binds to the G- rich box in the enhancer region of these genes. {ECO:0000250, ECO:0000269|PubMed:10448078, ECO:0000269|PubMed:12771217}.
Subcellular Location Nucleus {ECO:0000269|PubMed:10448078}.

ZNF281 CRISPR/Cas9 KO Plasmid (h) - sc-405466 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNF281 HDR Plasmid (h) - sc-405466-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNF281 Double Nickase Plasmid (h) - sc-405466-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNF281 Double Nickase Plasmid (h2) - sc-405466-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNF281 CRISPR Activation Plasmid (h) - sc-405466-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNF281 CRISPR Activation Plasmid (h2) - sc-405466-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNF281 Lentiviral Activation Particles (h) - sc-405466-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNF281 Lentiviral Activation Particles (h2) - sc-405466-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNF281 siRNA (h) - sc-88283 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ZNF281 shRNA Plasmid (h) - sc-88283-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ZNF281 shRNA (h) Lentiviral Particles - sc-88283-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ZNF281 RNAi - H00023528-R01V from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human
Western Blot: ZNF281 RNAi [H00023528-R01V] - Analysis of ZNF281 over-expressed 293 cell line, cotransfected with ZNF281 Validated Chimera RNAi or non-transfected control. Blot probed with H00023528-M01. GAPDH (36.1 kDa) used as loading control.

ZNF281 RNAi - H00023528-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU001591 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN23361 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23361 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06105 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06105

ZNF281 siRNA (Human) - CRH8333 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ZNF281 - MBS8215889 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ZNF281 (NM_012482.3) - SHH453528 from Creative biogene

Category siRNA
Species Reactivities Human

Human ZNF281 siRNA - orb268835 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ZNF281 shRNA Plasmid (Human) - CHH8333 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ZNF281 miRNA 3'UTR clone - MiUTR1H-11545 from Creative biogene

Species Reactivities Human
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