ERAP1

Gene Symbol ERAP1
Entrez Gene 51752
Alt Symbol A-LAP, ALAP, APPILS, ARTS-1, ARTS1, ERAAP, ERAAP1, PILS-AP, PILSAP
Species Human
Gene Type protein-coding
Description endoplasmic reticulum aminopeptidase 1
Other Description adipocyte-derived leucine aminopeptidase|aminopeptidase PILS|aminopeptidase regulator of TNFR1 shedding|endoplasmic reticulum aminopeptidase 1 delta-Exon-11 isoform|endoplasmic reticulum aminopeptidase 1 delta-Exon-13 isoform|endoplasmic reticulum aminopeptidase 1 delta-Exon-14 isoform|endoplasmic reticulum aminopeptidase 1 delta-Exon-15 isoform|endoplasmic reticulum aminopeptidase associated with antigen processing|puromycin-insensitive leucyl-specific aminopeptidase|type 1 tumor necrosis factor receptor shedding aminopeptidase regulator
Swissprots Q9NZ08 Q9UKY2 Q9UHF8 Q8TAD0 Q8NEL4 Q6UWY6 O60278
Accessions EAW96077 EAW96078 EAW96079 Q9NZ08 AB011097 BAA25451 AF106037 AAF07395 AF183569 AAF20384 AF222340 AAF34664 AK094985 AK222873 BAD96593 AK291636 BAF84325 AK310535 AL110186 AY028806 AAK37777 AY028807 AAK37778 AY358590 AAQ88953 BC030775 AAH30775 DA327238 DA704693 DC398730 JX962699 AGR86647 JX962700 AGR86648 JX962701 AGR86649 JX962702 AGR86650 KM357870 AIY60612 KM357871 AIY60613 KM357872 AIY60614 KM357873 AIY60615 KM357874 AIY60616 KM357875 AIY60617 KM357876 AIY60618 KM357877 AIY60619 KM357878 AIY60620 KM357879 AIY60621 KM357880 AIY60622 KM357881 AIY60623 KM357882 AIY60624 KM357883 AIY60625 KM357884 AIY60626 KM357885 AIY60627 KM357886 AIY60628 KM357887 AIY60629 KM357888 AIY60630 KM357889 AIY60631 KM357890 AIY60632 KM357891 AIY60633 LN608057 LN608058 LN608059 LN608060 XM_005272015 XP_005272072 XM_005272016 XP_005272073 XM_011543480 XP_011541782 XM_011543481 XP_011541783 XM_011543482 XP_011541784 XM_011543483 XP_011541785 XM_011543484 XP_011541786 XM_011543485 XP_011541787 XM_011543486 XP_011541788 XM_011543487 XP_011541789 NM_001040458 NP_001035548 NM_001198541 NP_001185470 NM_016442 NP_057526
Function Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I- binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney. {ECO:0000269|PubMed:15908954, ECO:0000269|PubMed:16286653, ECO:0000269|PubMed:21478864}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000305|PubMed:15908954}; Single-pass type II membrane protein {ECO:0000305|PubMed:15908954}.
Tissue Specificity Ubiquitous.

Alanine Aminopeptidase (AAP), Human, ELISA Kit - SEB065Hu from ARP American Research Products

Category ELISA Kit
Prices $685.00
Sizes 96 t
Sensitivity 0.51ng/mL
Range 1.56-100ng/mL

Endoplasmic reticulum aminopeptidase 1 (ERAP1), Human, ELISA Kit - CSB-EL007760HU from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

endoplasmic reticulum aminopeptidase 1, ELISA Kit - MBS937512 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.039 ng/ml.
Range 0.156 ng/ml-10 ng/ml.

Human Endoplasmic reticulum aminopeptidase 1(ERAP1) ELISA kit - CSB-EL007760HU from Cusabio

Category ELISA Kit
Sensitivity 0.039 ng/ml
Range 0.156 ng/ml-10 ng/ml

Custom Human Aminopeptidase PILS ELISA - ELH-ANPEPPILS from RayBiotech

Category ELISA Kit
Prices $615.00, $1,107.00, $2,460.00
Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human Aminopeptidase PILS ELISA Kit - orb319871 from Biorbyt

Category ELISA Kit
Prices $1,148.00, $1,981.00, $4,284.00
Sizes 96 assays, 192 assays, 480 assays

Human Aminopeptidase PILS ELISA - RAB1267 from Sigma-Aldrich

Prices $615.00
Sizes 1 kt

Human Endoplasmic reticulum aminopeptidase 1 (ERAP1) ELISA Kit - EKC33561 from Biomatik

Category ELISA Kit
Prices $705.00, $2,820.00, $5,288.00
Sizes 96 t, 5x96t, 10x96t
Sensitivity 0.039 ng/ml
Range 0.156 ng/ml-10 ng/ml

Custom Human Aminopeptidase PILS ELISA - ELH-ANPEPPILS-1 from RayBiotech

Category ELISA Kit
Prices $615.00, $1,107.00, $2,460.00
Sizes 1 plate kit, 2 plate kit, 5 plate kit
Sensitivity This has not yet been determined Looking for high sensitivity? Check out our new Ultrasensitive Biomarker Testing Service powered by SIMOA™ technology.

Human ERAP1 ELISA Kit - E013046 from Biobool

Category ELISA Kit
Sensitivity The minimum detectable dose of human ERAP1 is typically less than 0.039 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the m

ERAP1 ELISA Kit (Human) (OKCA00670) - OKCA00670 from Aviva Systems Biology

Category ELISA Kit
Prices $590.00
Sizes 96 wells
Sensitivity 0.039 ng/mL
Range 0.156 ng/mL-10 ng/mL

Endoplasmic Reticulum Aminopeptidase 1 (ERAP1), ELISA Kit - MBS9388844 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Endoplasmic Reticulum Aminopeptidase 1 (ERAP1), ELISA Kit - MBS9388852 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Endoplasmic Reticulum Aminopeptidase 1 (ERAP1), ELISA Kit - MBS9388840 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Endoplasmic Reticulum Aminopeptidase 1 (ERAP1), ELISA Kit - MBS9388843 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Endoplasmic Reticulum Aminopeptidase 1 (ERAP1), ELISA Kit - MBS9388845 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Endoplasmic Reticulum Aminopeptidase 1 (ERAP1), ELISA Kit - MBS9388846 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Endoplasmic Reticulum Aminopeptidase 1 (ERAP1), ELISA Kit - MBS9388850 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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