CCNC

Gene Symbol	CCNC
Entrez Gene	892
Alt Symbol	CycC
Species	Human
Gene Type	protein-coding
Description	cyclin C
Other Description	SRB11 homolog|cyclin-C|hSRB11
Swissprots	Q9H543 B4DPZ1 P24863
Accessions	AAC50825 EAW48465 EAW48466 EAW48467 EAW48468 P24863 AB125137 BAD00144 AK130983 AK222768 AK223247 AK291914 BAF84603 AK298558 BAG60753 BC010135 AAH10135 BC026272 AAH26272 BC030159 BC041123 AAH41123 BC050726 BC056153 AAH56153 BM788717 HQ448076 ADQ32557 M74091 XM_006715594 XP_006715657 XM_011536232 XP_011534534 NM_001013399 NP_001013417 NM_005190 NP_005181
Function	Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex. {ECO:0000269|PubMed:16595664, ECO:0000269|PubMed:8700522}.
Subcellular Location	Nucleus {ECO:0000305}.
Tissue Specificity	Highest levels in pancreas. High levels in heart, liver, skeletal muscle and kidney. Low levels in brain.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Cyclin-C (CCNC), Human, ELISA Kit - E01C1446 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Cyclin C (CCNC), ELISA Kit - MBS7231685 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cyclin C (CCNC), ELISA Kit - MBS9312762 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cyclin-C (CCNC), ELISA Kit - MBS7243530 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cyclin-C (CCNC), ELISA Kit - MBS7213069 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cyclin-C (CCNC), ELISA Kit - MBS7218462 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cyclin-C (CCNC), ELISA Kit - MBS7221823 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cyclin-C (CCNC), ELISA Kit - MBS7228012 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cyclin-C (CCNC), ELISA Kit - MBS7227246 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cyclin-C (CCNC), ELISA Kit - MBS7204491 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cyclin-C (CCNC), ELISA Kit - MBS7252623 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cyclin-C (CCNC), ELISA Kit - MBS7200937 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cyclin-C (CCNC), ELISA Kit - MBS7216320 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cyclin-C (CCNC), ELISA Kit - MBS7239121 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human CCNC ELISA Kit - E010530 from Biobool Category ELISA Kit

anti-Cyclin C antibody - ARG57347 from Arigo Biolaboratories Category ELISA Kit

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