CCNC

Gene Symbol	CCNC
Entrez Gene	892
Alt Symbol	CycC
Species	Human
Gene Type	protein-coding
Description	cyclin C
Other Description	SRB11 homolog|cyclin-C|hSRB11
Swissprots	Q9H543 B4DPZ1 P24863
Accessions	AAC50825 EAW48465 EAW48466 EAW48467 EAW48468 P24863 AB125137 BAD00144 AK130983 AK222768 AK223247 AK291914 BAF84603 AK298558 BAG60753 BC010135 AAH10135 BC026272 AAH26272 BC030159 BC041123 AAH41123 BC050726 BC056153 AAH56153 BM788717 HQ448076 ADQ32557 M74091 XM_006715594 XP_006715657 XM_011536232 XP_011534534 NM_001013399 NP_001013417 NM_005190 NP_005181
Function	Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex. {ECO:0000269|PubMed:16595664, ECO:0000269|PubMed:8700522}.
Subcellular Location	Nucleus {ECO:0000305}.
Tissue Specificity	Highest levels in pancreas. High levels in heart, liver, skeletal muscle and kidney. Low levels in brain.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Cyclin C protein (Tagged) - ab127682 from Abcam Category Protein Prices $235.00 Sizes 20 µg Source Baculovirus infected sf9 cells Species Human

Human Cyclin C full length protein - ab59893 from Abcam Category Protein Source E. coli Species Human

Human Cyclin C peptide - ab58437 from Abcam Category Peptide

CCNC / Cyclin C Antibody Blocking Peptide - LS-E835 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CCNC / Cyclin C Antibody Blocking Peptide - LS-E9297 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Cyclin C Recombinant Protein - H00000892-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Cyclin C Peptide - P2859 from Novus Biologicals Category Peptide Species Human

CCNC-Antibody-N-term-Blocking-peptide - BP11208a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Cyclin-C-CCNC-Antibody-C-term-Blocking-peptide - BP7835b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human cyclin C (CCNC) protein - orb176029 from Biorbyt Category Protein Prices $366.00, $400.00 Sizes 2 μl, 10 μl Species Human

Cyclin C - H00000892-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Cyclin C - H00000892-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CCNC fusion protein - ag5969 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

CCNC fusion protein - Ag6059 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

CCNC Human - PKPS-318 from NeoScientific Category Protein Prices $65.00, $169.00, $6,240.00 Sizes 2 µg, 10 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human Cyclin C Protein - BP002496-PKA-311 from Syd Labs Category Protein Prices $160.00, $4,800.00 Sizes 10 µg, 1 mg Source E. coli-derived. Species Human

CCNC Human Protein - GWB-BSP346 from Genway Biotech Category Protein Prices $75.00, $165.00, $6,100.00 Sizes 2 μg, 10 μg, 1000 μg Source Escherichia Coli. Species Human

Recombinant Human CCNC, His-tagged - CCNC-27518TH from Creative Biomart Category Protein Source E. coli

Recombinant Human CCNC, His-tagged - CCNC-10859H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Cyclin C - CCNC-07H from Creative Biomart Category Protein Source Escherichia Coli.

CCNC Human - LKP-755 from Reagent Proteins Category Protein Prices $348.00, $5,445.00 Sizes 10.00 µg, 1 mg Source E.Coli Species Human

CyclinC protein-GST fusion - 009-001-R77 from Rockland Immunochemicals Inc Category Protein Prices $499.00 Sizes 50 µg Species Human

CyclinC protein-GST fusion - 009-001-R77S from Rockland Immunochemicals Inc Category Protein Prices $265.00 Sizes 20 µg Species Human

Recombinant Cyclin-C(cic-1) - CSB-YP004810CXX CSB-EP004810CXX CSB-BP004810CXX CSB-MP004810CXX from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Caenorhabditis

Recombinant Human Cyclin-C(CCNC) - CSB-YP004810HU CSB-EP004810HU CSB-BP004810HU CSB-MP004810HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Search more