STEAP1

Gene Symbol STEAP1
Entrez Gene 26872
Alt Symbol PRSS24, STEAP
Species Human
Gene Type protein-coding
Description six transmembrane epithelial antigen of the prostate 1
Other Description metalloreductase STEAP1|six-transmembrane epithelial antigen of prostate 1
Swissprots A4D1E0 Q9UHE8 O95034
Accessions AAD15620 CAJ90613 EAL24166 EAL24167 EAW93749 EAW93750 EAW93751 EAW93752 Q9UHE8 AF186249 AAF17479 AK304076 BAG64983 AK308452 BC011802 AAH11802 BI549469 HQ448213 ADQ32693 NM_012449 NP_036581
Function Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity). {ECO:0000250}.
Subcellular Location Endosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Tissue Specificity Ubiquitously expressed. Highly expressed in prostate tumors. {ECO:0000269|PubMed:16609065}.
Top Pathways Mineral absorption

STEAP (B-4) - sc-271872 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
STEAP (B-4): sc-271872. Western blot analysis of STEAP expression in LNCaP whole cell lysate.

STEAP (H-105) - sc-25514 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
STEAP (H-105): sc-25514. Immunofluorescence staining of normal mouse intestine frozen section showing membrane staining.

STEAP (L-15) - sc-10262 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
STEAP (L-15): sc-10262. Western blot analysis of STEAP expression in LNCaP whole cell lysate.

STEAP (N-15) - sc-10260 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
STEAP (N-15): sc-10260. Immunofluorescence staining of methanol-fixed LNCaP cells showing membrane staining.

Anti-STEAP1 antibody - ab3679 from Abcam

Prices $378.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-STEAP1 antibody - ab123417 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-STEAP1 antibody (ab123417) at 1/100 dilution + WiDr cell line lysate at 35 µg

Anti-STEAP1 antibody - ab57147 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-STEAP1 antibody [J2D2] - ab117454 from Abcam

Prices $384.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone J2D2
Overlay histogram showing LnCAP cells stained with ab117454 (red line). The cells were fixed with 4% paraformaldehyde (10 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab117454, 1μg/1x106 cells) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-mouse IgG (H&L) (ab150113) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG2b [PLPV219] (ab91366, 1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. This antibody gave a positive signal in LnCAP cells fixed with 80% methanol (5 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-STEAP1 / STEAP Antibody (aa1-72) - LS-C126326 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-STEAP1 / STEAP Antibody - LS-C211342 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-STEAP1 / STEAP Antibody (HRP) - LS-C211347 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-STEAP1 / STEAP Antibody (Biotin) - LS-C211348 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-STEAP1 / STEAP Antibody (FITC) - LS-C211349 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-STEAP1 / STEAP Antibody (aa1-31, AP) - LS-C270544 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STEAP1 / STEAP Antibody (aa1-31, APC) - LS-C270545 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STEAP1 / STEAP Antibody (aa1-31, PE) - LS-C270546 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STEAP1 / STEAP Antibody (aa106-155) - LS-C135043 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
STEAP1 antibody LS-C135043 Western blot of THP-1 cell lysate.

Anti-STEAP1 / STEAP Antibody (aa1-340, Azide-free) - LS-C328759 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-STEAP1 / STEAP Antibody (aa31-80) - LS-C291740 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-STEAP1 / STEAP Antibody (aa1-31) - LS-C330181 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-STEAP1 / STEAP Antibody (Asp31) - LS-C177286 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of STEAP1 (D31) pAb in paraffin-embedded human prostate carcinoma tissue.

Anti-STEAP1 / STEAP Antibody (aa1-31) - LS-C161556 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
STEAP1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human skeletal muscle followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-STEAP1 / STEAP Antibody (N-Terminus) IHC-plus™ - LS-B1260 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-STEAP1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1260 concentration 10 ug/ml.

Anti-STEAP1 / STEAP Antibody (C-Terminus) IHC-plus™ - LS-B2828 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-STEAP1 antibody IHC of human lung, bronchiole. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2828 concentration 5 ug/ml.

Anti-STEAP1 / STEAP Antibody (Internal) IHC-plus™ - LS-B3801 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-STEAP1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3801 concentration 5 ug/ml.
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