Gene Symbol | STEAP1 |
---|---|
Entrez Gene | 26872 |
Alt Symbol | PRSS24, STEAP |
Species | Human |
Gene Type | protein-coding |
Description | six transmembrane epithelial antigen of the prostate 1 |
Other Description | metalloreductase STEAP1|six-transmembrane epithelial antigen of prostate 1 |
Swissprots | A4D1E0 Q9UHE8 O95034 |
Accessions | AAD15620 CAJ90613 EAL24166 EAL24167 EAW93749 EAW93750 EAW93751 EAW93752 Q9UHE8 AF186249 AAF17479 AK304076 BAG64983 AK308452 BC011802 AAH11802 BI549469 HQ448213 ADQ32693 NM_012449 NP_036581 |
Function | Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity). {ECO:0000250}. |
Subcellular Location | Endosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Tissue Specificity | Ubiquitously expressed. Highly expressed in prostate tumors. {ECO:0000269|PubMed:16609065}. |
Top Pathways | Mineral absorption |