Gene Symbol |
STEAP1
|
Entrez Gene |
26872
|
Alt Symbol |
PRSS24, STEAP
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
six transmembrane epithelial antigen of the prostate 1
|
Other Description |
metalloreductase STEAP1|six-transmembrane epithelial antigen of prostate 1
|
Swissprots |
A4D1E0 Q9UHE8 O95034
|
Accessions |
AAD15620 CAJ90613 EAL24166 EAL24167 EAW93749 EAW93750 EAW93751 EAW93752 Q9UHE8 AF186249 AAF17479 AK304076 BAG64983 AK308452 BC011802 AAH11802 BI549469 HQ448213 ADQ32693 NM_012449 NP_036581
|
Function |
Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity). {ECO:0000250}.
|
Subcellular Location |
Endosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
Tissue Specificity |
Ubiquitously expressed. Highly expressed in prostate tumors. {ECO:0000269|PubMed:16609065}.
|
Top Pathways |
Mineral absorption
|