LYNX1

Gene Symbol	LYNX1
Entrez Gene	66004
Alt Symbol	SLURP2
Species	Human
Gene Type	protein-coding
Description	Ly6/neurotoxin 1
Other Description	Ly-6 neurotoxin-like protein 1|SLURP-2|ly-6/neurotoxin-like protein 1|secreted Ly-6/uPAR domain-containing protein 2|secreted Ly-6/uPAR-related protein 2|secreted Ly6/uPAR related protein 2
Swissprots	G3XAC2 Q86SR0 D3DWI7 Q9BZG9
Accessions	EAW82299 EAW82301 EAW82302 EAW82303 EAW82304 EAW82306 Q9BZG9 AB081838 BAC56859 AF321824 AAK01642 AI494395 AK123335 AK126845 AL353948 AW449754 AY358417 AAQ88783 AY587277 AAT00512 BC014560 BC047923 BG701653 BI603715 BM172253 BM671222 BQ685632 BU683767 DB501423 HY110957 XM_011517238 XP_011515540 NM_023946 NP_076435 NM_177457 NP_803252 NM_177458 NP_803253 NM_177476 NP_803429 NM_177477 NP_803430
Function	Acts in different tissues through interaction to nicotinic acetylcholine receptors (nAChRs). In brain, isoform 2 modulates functional properties of nAChRs to prevent excessive excitation, and hence neurodegeneration. Enhances desensitization by increasing both the rate and extent of desensitization of alpha(4)beta(2) nAChRs and slowing recovery from desensitization. Promotes large amplitude ACh-evoked currents through alpha(4)beta(2) nAChRs (By similarity). Prevents plasticity in the primary visual cortex late in life (By similarity). In keratinocytes, isoform 3 delays differentiation and prevents apoptosis. {ECO:0000250, ECO:0000269|PubMed:16575903}.
Subcellular Location	Isoform 3: Secreted.
Tissue Specificity	Isoform 3 is expressed at highest levels in cervix and esophagus, followed by adult and fetal skin. Expressed at lower levels in brain, lung, stomach, small intestine, colon, rectum, uterus, and thymus. Not detected in spleen nor bone marrow. In the epidermis, predominantly produced by keratinocytes of the suprabasal epidermal compartment (at protein level). In attached gingiva, produced at highest levels by basal cells located in the lowermost epithelial layers (at protein level). Up- regulated 3-fold in psoriatic lesional skin. Detected in serum (at protein level). {ECO:0000269|PubMed:12573258, ECO:0000269|PubMed:16575903}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Lynx1 (M-17) - sc-15302 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Lynx1 (T-15) - sc-23060 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-LYNX1 antibody - ab121772 from Abcam Prices $443.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-LYNX1 antibody - ab118716 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-LYNX1 antibody [EPR6829] - ab125035 from Abcam Prices $313.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR6829

Anti-LYNX1 Antibody (Internal, clone EPR6829) - LS-C138996 from LifeSpan Bioscience Prices $395.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR6829

Anti-LYNX1 Antibody (aa40-89) - LS-C145872 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

LYNX1 Antibody - NBP1-80739 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-LYNX1 antibody produced in rabbit - HPA023711 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

LYNX1 Antibody : APC (OASB00555) - OASB00555 from Aviva Systems Biology Prices $258.00 Sizes 100 µg Host Rat Clonality Monoclonal Clone D7

LYNX1 antibody [EPR6829] - GTX63280 from GeneTex Host Rabbit Clonality Monoclonal Clone EPR6829

LYNX1 antibody - 13373-1-AP from Proteintech Group Prices $279.00 Sizes con: 41 μg/150μl Host Rabbit Clonality Polyclonal

LYNX1 - MBS6003582 from MyBioSource Clonality Monoclonal Clone EPR6829

Anti-LYNX1 (aa 23-97) polyclonal antibody - DPABH-20091 from Creative Diagnostics Host Rabbit Clonality Polyclonal

LYNX1 antibody - 13373-1-AP from Acris Antibodies Prices $270.00 Sizes 150 µl Host Rabbit Clonality Polyclonal

LYNX1 antibody - orb185099 from Biorbyt Prices $255.00, $340.00 Sizes 100 μg, 200 μg Host Rabbit Clonality Polyclonal

Lynx1 (FL-97) - sc-367147 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

ANTI-LYNX1 (CENTER) antibody produced in rabbit - SAB1304441 from Sigma-Aldrich Prices $336.50 Sizes 400 µl Clonality Polyclonal

Recombinant Anti-human Lynx1 Intrabody [(D-Arg) 9 ] - IAB-B019(A) from Creative Biolabs Host Mouse

Recombinant Anti-human Lynx1 Intrabody [+36 GFP] - IAB-B019(G) from Creative Biolabs Host Mouse

Recombinant Anti-human Lynx1 Intrabody [Tat] - IAB-B019(T) from Creative Biolabs Host Mouse

LYNX1 antibody - center region (OAAB12597) - OAAB12597 from Aviva Systems Biology Host Rabbit Clonality Polyclonal

Anti-LYNX1 Antibody (aa40-89, HRP) - LS-C465367 from LifeSpan Bioscience Host Rabbit Clonality Polyclonal

Anti-LYNX1 Antibody (aa40-89, FITC) - LS-C465366 from LifeSpan Bioscience Host Rabbit Clonality Polyclonal

Anti-LYNX1 Antibody (aa40-89, Biotin) - LS-C465365 from LifeSpan Bioscience Host Rabbit Clonality Polyclonal

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