LYNX1

Gene Symbol LYNX1
Entrez Gene 66004
Alt Symbol SLURP2
Species Human
Gene Type protein-coding
Description Ly6/neurotoxin 1
Other Description Ly-6 neurotoxin-like protein 1|SLURP-2|ly-6/neurotoxin-like protein 1|secreted Ly-6/uPAR domain-containing protein 2|secreted Ly-6/uPAR-related protein 2|secreted Ly6/uPAR related protein 2
Swissprots G3XAC2 Q86SR0 D3DWI7 Q9BZG9
Accessions EAW82299 EAW82301 EAW82302 EAW82303 EAW82304 EAW82306 Q9BZG9 AB081838 BAC56859 AF321824 AAK01642 AI494395 AK123335 AK126845 AL353948 AW449754 AY358417 AAQ88783 AY587277 AAT00512 BC014560 BC047923 BG701653 BI603715 BM172253 BM671222 BQ685632 BU683767 DB501423 HY110957 XM_011517238 XP_011515540 NM_023946 NP_076435 NM_177457 NP_803252 NM_177458 NP_803253 NM_177476 NP_803429 NM_177477 NP_803430
Function Acts in different tissues through interaction to nicotinic acetylcholine receptors (nAChRs). In brain, isoform 2 modulates functional properties of nAChRs to prevent excessive excitation, and hence neurodegeneration. Enhances desensitization by increasing both the rate and extent of desensitization of alpha(4)beta(2) nAChRs and slowing recovery from desensitization. Promotes large amplitude ACh-evoked currents through alpha(4)beta(2) nAChRs (By similarity). Prevents plasticity in the primary visual cortex late in life (By similarity). In keratinocytes, isoform 3 delays differentiation and prevents apoptosis. {ECO:0000250, ECO:0000269|PubMed:16575903}.
Subcellular Location Isoform 3: Secreted.
Tissue Specificity Isoform 3 is expressed at highest levels in cervix and esophagus, followed by adult and fetal skin. Expressed at lower levels in brain, lung, stomach, small intestine, colon, rectum, uterus, and thymus. Not detected in spleen nor bone marrow. In the epidermis, predominantly produced by keratinocytes of the suprabasal epidermal compartment (at protein level). In attached gingiva, produced at highest levels by basal cells located in the lowermost epithelial layers (at protein level). Up- regulated 3-fold in psoriatic lesional skin. Detected in serum (at protein level). {ECO:0000269|PubMed:12573258, ECO:0000269|PubMed:16575903}.

LYNX1 Antibody Blocking Peptide - LS-E21483 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

LYNX1-Antibody-Center-Blocking-Peptide - BP17173c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

LYNX1 fusion protein - Ag4195 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human LYNX1, GST-tagged - LYNX1-664H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human Ly-6/neurotoxin-like protein 1(LYNX1) - CSB-YP861187HU CSB-EP861187HU CSB-BP861187HU CSB-MP861187HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Recombinant Human Secreted Ly-6/uPAR-related protein 2(SLURP2) - CSB-YP773019HU CSB-EP773019HU CSB-BP773019HU CSB-MP773019HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

LYNX1 (transcript variant 1) - TP307126 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
LYNX1

LYNX1 (transcript variant SLURP2) - TP311711 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
LYNX1

Recombinant Human LYNX1 protein, His-tagged - LYNX1-12H from Creative Biomart

Category Protein
Source HEK293
Species Human

Recombinant Human LYNX1 protein, MYC/DDK-tagged - LYNX1-13H from Creative Biomart

Category Protein
Source HEK293
Species Human

Recombinant Human LYNX1 protein, MYC/DDK-tagged - LYNX1-14H from Creative Biomart

Category Protein
Source HEK293
Species Human

LYNX1 Protein - NBP1-80739PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

LYNX1 Peptide, Human - M34GP09020H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Ly-6/neurotoxin-like protein 1 (LYNX1), Recombinant Protein - MBS1281213 from MyBioSource

Category Protein
Prices $845.00, $845.00, $1,070.00, $1,070.00, $1,220.00, $1,220.00, $1,675.00, $1,675.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

Recombinant Human SLURP2 Protein (23-97 aa), His-tagged - SLURP2-2440H from Creative Biomart

Category Protein
Source Yeast
Species Human
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