Gene Symbol | PLA2G12A |
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Entrez Gene | 81579 |
Alt Symbol | GXII, PLA2G12, ROSSY |
Species | Human |
Gene Type | protein-coding |
Description | phospholipase A2, group XIIA |
Other Description | GXII sPLA2|group XII secreted phospholipase A2|group XIIA secreted phospholipase A2|group XIIA secretory phospholipase A2|phosphatidylcholine 2-acylhydrolase 12A|phospholipase A2, group XII|sPLA2-XII |
Swissprots | Q9BZ89 Q9BZM1 |
Accessions | CAI72089 EAX06246 EAX06247 EAX06248 EAX06249 Q9BZM1 AF306567 AAG50243 AF332892 AAG50289 AK075389 BAC11589 AK313081 BAG35907 AY359024 AAQ89383 BC017218 AAH17218 BI667755 DQ892725 ABM83651 DQ896860 ABM87859 NM_030821 NP_110448 |
Function | PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Does not exhibit detectable activity toward sn-2-arachidonoyl- or linoleoyl- phosphatidylcholine or -phosphatidylethanolamine. {ECO:0000269|PubMed:12522102}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:12522102}. Cytoplasm {ECO:0000269|PubMed:12522102}. |
Tissue Specificity | Abundantly expressed in heart, skeletal muscle, kidney, liver and pancreas. |
Top Pathways | Vascular smooth muscle contraction, Pancreatic secretion, Fat digestion and absorption, Ether lipid metabolism, Glycerophospholipid metabolism |
group XIIA sPLA 2 (E-9) - sc-514423 from Santa Cruz Biotechnology
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group XIIA sPLA 2 (W-12) - sc-104302 from Santa Cruz Biotechnology
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group XIIA sPLA 2 (K-15) - sc-104300 from Santa Cruz Biotechnology
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group XIIA sPLA 2 (SP-34) - sc-134352 from Santa Cruz Biotechnology
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Anti-Phospholipase A2 XII antibody - ab169926 from Abcam
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Anti-Phospholipase A2 XII antibody - ab129791 from Abcam
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Anti-Phospholipase A2 XII antibody - ab97333 from Abcam
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Anti-Phospholipase A2 XII antibody - ab47121 from Abcam
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Anti-Phospholipase A2 XII antibody - ab57867 from Abcam
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Anti-Phospholipase A2 XII antibody [3H2C11] - ab201944 from Abcam
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Anti-Phospholipase A2 XII antibody [7C7C9] - ab201950 from Abcam
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Anti-PLA2G12A Antibody (aa55-83, AP) - LS-C266442 from LifeSpan Bioscience
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Anti-PLA2G12A Antibody (aa55-83, Biotin) - LS-C266446 from LifeSpan Bioscience
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Anti-PLA2G12A Antibody (aa55-83, APC) - LS-C266445 from LifeSpan Bioscience
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Anti-PLA2G12A Antibody (aa55-83, FITC) - LS-C266447 from LifeSpan Bioscience
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Anti-PLA2G12A Antibody (aa55-83, PE) - LS-C266448 from LifeSpan Bioscience
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Anti-PLA2G12A Antibody (aa55-83, Azide-free, HRP) - LS-C266449 from LifeSpan Bioscience
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Anti-PLA2G12A Antibody (aa54-83) - LS-C324080 from LifeSpan Bioscience
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Anti-PLA2G12A Antibody (aa22-115) - LS-C186241 from LifeSpan Bioscience
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Anti-PLA2G12A Antibody (aa55-83) - LS-C163755 from LifeSpan Bioscience
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Phospholipase A2 XII Antibody (3H2C11) - NBP2-37255 from Novus Biologicals
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Phospholipase A2 XII Antibody (7C7C9) - NBP2-37258 from Novus Biologicals
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Phospholipase A2 XII Antibody - NBP2-19808 from Novus Biologicals
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Phospholipase A2 XII Antibody - NBP1-31693 from Novus Biologicals
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Phospholipase A2 XII Antibody (1D11) - H00081579-M01 from Novus Biologicals
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