Gene Symbol | PLA2G12A |
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Entrez Gene | 81579 |
Alt Symbol | GXII, PLA2G12, ROSSY |
Species | Human |
Gene Type | protein-coding |
Description | phospholipase A2, group XIIA |
Other Description | GXII sPLA2|group XII secreted phospholipase A2|group XIIA secreted phospholipase A2|group XIIA secretory phospholipase A2|phosphatidylcholine 2-acylhydrolase 12A|phospholipase A2, group XII|sPLA2-XII |
Swissprots | Q9BZ89 Q9BZM1 |
Accessions | CAI72089 EAX06246 EAX06247 EAX06248 EAX06249 Q9BZM1 AF306567 AAG50243 AF332892 AAG50289 AK075389 BAC11589 AK313081 BAG35907 AY359024 AAQ89383 BC017218 AAH17218 BI667755 DQ892725 ABM83651 DQ896860 ABM87859 NM_030821 NP_110448 |
Function | PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Does not exhibit detectable activity toward sn-2-arachidonoyl- or linoleoyl- phosphatidylcholine or -phosphatidylethanolamine. {ECO:0000269|PubMed:12522102}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:12522102}. Cytoplasm {ECO:0000269|PubMed:12522102}. |
Tissue Specificity | Abundantly expressed in heart, skeletal muscle, kidney, liver and pancreas. |
Top Pathways | Vascular smooth muscle contraction, Pancreatic secretion, Fat digestion and absorption, Ether lipid metabolism, Glycerophospholipid metabolism |
Human Phospholipase A2 XII full length protein - ab135014 from Abcam
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Human Phospholipase A2 XII full length protein - ab63848 from Abcam
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PLA2G12A Antibody Blocking Peptide - LS-E4341 from LifeSpan Bioscience
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Recombinant Human Phospholipase A2 XII Protein - H00081579-P01 from Novus Biologicals
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Recombinant Human Phospholipase A2 XII Protein - H00081579-Q01 from Novus Biologicals
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PLA2G12A-Antibody-Center-Blocking-Peptide - BP16639c from Abgent, a WuXi AppTec company
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PLA2G12 Protein (OPPA00849) - OPPA00849 from Aviva Systems Biology
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Human Secreted Phospholipase A2-XII protein - orb90223 from Biorbyt
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PLA2G12A - H00081579-P01-10 from Acris Antibodies
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PLA2G12A - H00081579-P01-25 from Acris Antibodies
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PLA2G12A - H00081579-Q01-10 from Acris Antibodies
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PLA2G12A - H00081579-Q01-25 from Acris Antibodies
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Secreted Phospholipase A2-XII, Human Recombinant - 228-11266-1 from RayBiotech
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Recombinant Human PLA2G12 - 228-11266-2 from RayBiotech
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Recombinant Human PLA2G12 - 228-11266-3 from RayBiotech
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PLA2G12A fusion protein - Ag8722 from Proteintech Group
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PLA2G12A fusion protein - Ag8890 from Proteintech Group
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PLA2G12 Human - ENPS-337 from NeoScientific
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Recombinant Human Secreted Phospholipase A2-XII - BP000891-ENZ-330 from Syd Labs
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PLA2G12A Human Recombinant Protein - GWB-PS93CF from Genway Biotech
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Recombinant Human Phospholipase A2, Group XIIA, His-tagged - PLA2G12A-72H from Creative Biomart
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Recombinant Human PLA2G12A, His-tagged - PLA2G12A-30734TH from Creative Biomart
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Recombinant Human PLA2G12A, GST-tagged - PLA2G12A-1749H from Creative Biomart
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PLA2G12 Human - JNV-770 from Reagent Proteins
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Recombinant human Group XIIA secretory phospholipase A2 - CSB-EP863638HU CSB-BP863638HU CSB-MP863638HU from Cusabio
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