TNFRSF6B

Gene Symbol TNFRSF6B
Entrez Gene 8771
Alt Symbol DCR3, DJ583P15.1.1, M68, M68E, TR6
Species Human
Gene Type protein-coding
Description tumor necrosis factor receptor superfamily, member 6b, decoy
Other Description decoy receptor 3|decoy receptor for Fas ligand|tumor necrosis factor receptor superfamily member 6B
Swissprots O95407
Accessions AAF35244 CCQ43788 EAW75242 EAW75243 EAW75244 EAW75246 EAW75247 EAW75248 O95407 AF104419 AAD03056 AF134240 AAD29688 AF217794 AAF33686 AW204999 AY124378 AAM94172 AY124379 AAM94173 AY358279 AAQ88646 BC017065 AAH17065 BC034349 AAH34349 BM759033 NM_003823 NP_003814 NM_032945
Function Decoy receptor that can neutralize the cytotoxic ligands TNFS14/LIGHT, TNFSF15 and TNFSF6/FASL. Protects against apoptosis. {ECO:0000269|PubMed:21300286}.
Subcellular Location Secreted.
Tissue Specificity Detected in fetal lung, brain and liver. Detected in adult stomach, spinal cord, lymph node, trachea, spleen, colon and lung. Highly expressed in several primary tumors from colon, stomach, rectum, esophagus and in SW480 colon carcinoma cells.
Top Pathways Cytokine-cytokine receptor interaction

TNFRSF6B-Over-expression-Lysate - LY14945a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag TNFRSF6B (arrow) using his tag antibody. 293T cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the TNFRSF6B gene‘

TNFRSF6B overexpression lysate - LY418407 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

TNFRSF6B overexpression lysate - LY429165 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

TNFRSF6B 293 Cell Lysate - 408585 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg
Disease Tumor

DcR3/TNFRSF6B Overexpression Lysate (Native) - NBL1-17158 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: DcR3 Overexpression Lysate (Adult Normal) [NBL1-17158] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for DcR3.

DcR3 (h): 293 Lysate - sc-113152 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

DcR3 (h2): 293T Lysate - sc-113839 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

TNFRSF6B Over-expression Lysate Product - GWB-7ECFCB from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

TNFRSF6B Over-expression Lysate Product - GWB-639EE6 from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

Human DCR3 / TNFRSF6B Insect Cell Lysate (WB positive control) - 10224-H02BL-300 from Sino Biological

Category Cell Lysate
Prices $195.00
Sizes 300 µg
Species Human

DcR3/TNFRSF6B Overexpression Lysate (Native) - NBP2-11314 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg

DcR3/TNFRSF6B Overexpression Lysate (Native) - NBP2-10548 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: DcR3 Overexpression Lysate (Adult Normal) [NBP2-10548] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for DcR3.

Human DCR3 Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb175294 from Biorbyt

Category Cell Lysate
Prices $604.00
Sizes 300 μg
Species Human

Panoply™ Human TNFRSF6B Knockdown Stable Cell Line - CSC-DC016368 from Creative biogene

Category Cell Line
Species Human
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