TNFRSF6B

Gene Symbol	TNFRSF6B
Entrez Gene	8771
Alt Symbol	DCR3, DJ583P15.1.1, M68, M68E, TR6
Species	Human
Gene Type	protein-coding
Description	tumor necrosis factor receptor superfamily, member 6b, decoy
Other Description	decoy receptor 3|decoy receptor for Fas ligand|tumor necrosis factor receptor superfamily member 6B
Swissprots	O95407
Accessions	AAF35244 CCQ43788 EAW75242 EAW75243 EAW75244 EAW75246 EAW75247 EAW75248 O95407 AF104419 AAD03056 AF134240 AAD29688 AF217794 AAF33686 AW204999 AY124378 AAM94172 AY124379 AAM94173 AY358279 AAQ88646 BC017065 AAH17065 BC034349 AAH34349 BM759033 NM_003823 NP_003814 NM_032945
Function	Decoy receptor that can neutralize the cytotoxic ligands TNFS14/LIGHT, TNFSF15 and TNFSF6/FASL. Protects against apoptosis. {ECO:0000269|PubMed:21300286}.
Subcellular Location	Secreted.
Tissue Specificity	Detected in fetal lung, brain and liver. Detected in adult stomach, spinal cord, lymph node, trachea, spleen, colon and lung. Highly expressed in several primary tumors from colon, stomach, rectum, esophagus and in SW480 colon carcinoma cells.
Top Pathways	Cytokine-cytokine receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DcR3 full length protein - ab185255 from Abcam Category Protein Prices $927.00 Sizes 50 µg Source HEK 293 cells Species Human

DcR3 peptide - ab8437 from Abcam Category Peptide Prices $181.00 Sizes 50 µg

Human DcR3 full length protein - ab176068 from Abcam Category Protein Source E. coli Species Human

Human DcR3 protein fragment - ab157279 from Abcam Category Protein Source HEK 293 cells Species Human

Human DcR3 protein fragment - ab160177 from Abcam Category Protein Source Wheat germ Species Human

TNFRSF6B / DCR3 Antibody Blocking Peptide - LS-E66 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TNFRSF6B / DCR3 Antibody Blocking Peptide - LS-E29900 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

DcR3/TNFRSF6B Partial Recombinant Protein - H00008771-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human DcR3/TNFRSF6B Protein - NBP2-22907 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

DcR3/TNFRSF6B Blocking Peptide - NBP1-76909PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

TNFRSF6B-Antibody-N-term-Blocking-peptide - BP10136a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DcR3 peptide - GTX28437 from GeneTex Category Peptide Prices $179.00 Sizes 50 μg Species Human

Recombinant Human DcR3/TNFRSF6B Fc Chimera, CF - 142-DC-100 from R&D Systems Category Protein Source Spodoptera frugiperda, Sf 21 (baculovirus)-derived

TNFRSF6B Protein Lysate (APL10183) - APL10183 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

TNFRSF6B protein (His tag) - 80R-3549 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

TNFRSF6B / DCR3 - H00008771-H01 from Acris Antibodies Category Protein Prices $570.00 Sizes 2 µg Source Human HEK293T cells Species Human

TNFRSF6B / DCR3 - H00008771-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TNFRSF6B / DCR3 - H00008771-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TNFRSF6B / DCR3 Control Peptide - AP30281CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

TNFRSF6B, 30-300aa, Human, His tag, E.coli - 01-P2416 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

DcR3 Peptide - 2140P from ProSci Category Peptide Species Human

DcR3 Recombinant Protein - 96-740 from ProSci Category Protein Prices $450.00 Sizes 50 µg Source HEK293 cells Species Human

TNFRSF6B fusion protein - ag19771 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

TNFRSF6B fusion protein - ag19781 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human DcR3, HIgG1 Fc-tagged - DcR3-678H from Creative Biomart Category Protein Source CHO cell Species Human

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