Gene Symbol | PHACTR1 |
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Entrez Gene | 221692 |
Alt Symbol | RPEL, RPEL1, dJ257A7.2 |
Species | Human |
Gene Type | protein-coding |
Description | phosphatase and actin regulator 1 |
Other Description | RPEL repeat containing 1 |
Swissprots | Q9C0D0 Q5JSJ2 Q3MJ93 A8K1V2 |
Accessions | EAW55320 EAW55321 Q9C0D0 AA809685 AB051520 BAB21824 AK090769 BAG52223 AK290017 BAF82706 AK295263 BAG58252 BC047159 BC067280 BC101526 AAI01527 BC101528 AAI01529 BF026507 BQ434462 DA253448 DA330657 XM_005248933 XP_005248990 XM_005248934 XP_005248991 XM_005248935 XP_005248992 XM_005248936 XP_005248993 XM_005248937 XP_005248994 XM_006715021 XP_006715084 XM_011514390 XP_011512692 XM_011514391 XP_011512693 XM_011514392 XP_011512694 NM_001242648 NP_001229577 NM_030948 NP_112210 |
Function | Binds actin monomers (G actin) and plays a role in the reorganization of the actin cytoskeleton and in formation of actin stress fibers. Plays a role in cell motility. Plays a role in the formation of tubules by endothelial cells. Regulates PPP1CA activity. Required for normal cell survival. {ECO:0000269|PubMed:21798305, ECO:0000269|PubMed:21939755}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Nucleus {ECO:0000250}. Note=Enriched at synapses (By similarity). Cytoplasmic in resting cells, and is imported into the nucleus upon serum stimulation. Interaction with actin prevents nuclear import (By similarity). {ECO:0000250}. |
Tissue Specificity | Detected in umbilical vein endothelial cells. {ECO:0000269|PubMed:21939755}. |
PHACTR1 (D-13) - sc-103813 from Santa Cruz Biotechnology
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Anti-PHACTR1 antibody - ab84646 from Abcam
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Anti-PHACTR1 Antibody (aa468-517) IHC-plus⢠- LS-B4000 from LifeSpan Bioscience
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PHACTR1 Antibody - NBP1-84232 from Novus Biologicals
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PHACTR1 Antibody - NBP1-85186 from Novus Biologicals
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PHACTR1 Antibody - NBP1-56787 from Novus Biologicals
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Anti-PHACTR1 antibody produced in rabbit - HPA029756 from Sigma-Aldrich
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Anti-PHACTR1 antibody produced in rabbit - HPA029757 from Sigma-Aldrich
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Anti-PHACTR1 (51-65) antibody produced in rabbit - SAB1103712 from Sigma-Aldrich
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Anti-PHACTR1 antibody produced in rabbit - HPA029755 from Sigma-Aldrich
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Anti-PHACTR1 antibody produced in rabbit - SAB2101783 from Sigma-Aldrich
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PHACTR1 antibody - middle region (ARP55397_P050) - ARP55397_P050 from Aviva Systems Biology
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PHACTR1 antibody - 70R-4246 from Fitzgerald
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PHACTR1 antibody - 23446-1-AP from Acris Antibodies
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PHACTR1 Antibody - 27-011 from ProSci
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PHACTR1 antibody - 23446-1-AP from Proteintech Group
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PHACTR1 Antibody - GWB-MT819I from Genway Biotech
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Anti-PHACTR1 monoclonal antibody - DCABH-16393 from Creative Diagnostics
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PHACTR1 Polyclonal Antibody - PA5-35948 from Thermo Fisher Scientific
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PHACTR1 antibody - GTX122251 from GeneTex
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PHACTR1 antibody, Internal - GTX45287 from GeneTex
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PHACTR1-antibody-middle-region-AI13789 - AI13789 from Abgent, a WuXi AppTec company
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PHACTR1 (E-2) - sc-514800 from Santa Cruz Biotechnology
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PHACTR1, Polyclonal Antibody - MBS839960 from MyBioSource
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PHACTR1 - A9567 from NeoScientific
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