PHACTR1

Gene Symbol PHACTR1
Entrez Gene 221692
Alt Symbol RPEL, RPEL1, dJ257A7.2
Species Human
Gene Type protein-coding
Description phosphatase and actin regulator 1
Other Description RPEL repeat containing 1
Swissprots Q9C0D0 Q5JSJ2 Q3MJ93 A8K1V2
Accessions EAW55320 EAW55321 Q9C0D0 AA809685 AB051520 BAB21824 AK090769 BAG52223 AK290017 BAF82706 AK295263 BAG58252 BC047159 BC067280 BC101526 AAI01527 BC101528 AAI01529 BF026507 BQ434462 DA253448 DA330657 XM_005248933 XP_005248990 XM_005248934 XP_005248991 XM_005248935 XP_005248992 XM_005248936 XP_005248993 XM_005248937 XP_005248994 XM_006715021 XP_006715084 XM_011514390 XP_011512692 XM_011514391 XP_011512693 XM_011514392 XP_011512694 NM_001242648 NP_001229577 NM_030948 NP_112210
Function Binds actin monomers (G actin) and plays a role in the reorganization of the actin cytoskeleton and in formation of actin stress fibers. Plays a role in cell motility. Plays a role in the formation of tubules by endothelial cells. Regulates PPP1CA activity. Required for normal cell survival. {ECO:0000269|PubMed:21798305, ECO:0000269|PubMed:21939755}.
Subcellular Location Cytoplasm {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Nucleus {ECO:0000250}. Note=Enriched at synapses (By similarity). Cytoplasmic in resting cells, and is imported into the nucleus upon serum stimulation. Interaction with actin prevents nuclear import (By similarity). {ECO:0000250}.
Tissue Specificity Detected in umbilical vein endothelial cells. {ECO:0000269|PubMed:21939755}.

PHACTR1 CRISPR/Cas9 KO Plasmid (h) - sc-417747 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHACTR1 HDR Plasmid (h) - sc-417747-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHACTR1 Double Nickase Plasmid (h) - sc-417747-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHACTR1 Double Nickase Plasmid (h2) - sc-417747-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHACTR1 CRISPR Activation Plasmid (h) - sc-417747-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHACTR1 CRISPR Activation Plasmid (h2) - sc-417747-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHACTR1 Lentiviral Activation Particles (h) - sc-417747-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHACTR1 Lentiviral Activation Particles (h2) - sc-417747-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHACTR1 siRNA (h) - sc-95456 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PHACTR1 shRNA Plasmid (h) - sc-95456-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PHACTR1 shRNA (h) Lentiviral Particles - sc-95456-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU049701 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16704 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16704 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00428 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00428

PHACTR1 siRNA (Human) - CRJ6532 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PHACTR1 (NM_030948.2) - SHH374468 from Creative biogene

Category siRNA
Species Reactivities Human

Human PHACTR1 siRNA - orb277033 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PHACTR1 shRNA Plasmid (Human) - CHJ6532 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PHACTR1 miRNA 3'UTR clone - MiUTR3H-10166 from Creative biogene

Species Reactivities Human
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