PHACTR1

Gene Symbol	PHACTR1
Entrez Gene	221692
Alt Symbol	RPEL, RPEL1, dJ257A7.2
Species	Human
Gene Type	protein-coding
Description	phosphatase and actin regulator 1
Other Description	RPEL repeat containing 1
Swissprots	Q9C0D0 Q5JSJ2 Q3MJ93 A8K1V2
Accessions	EAW55320 EAW55321 Q9C0D0 AA809685 AB051520 BAB21824 AK090769 BAG52223 AK290017 BAF82706 AK295263 BAG58252 BC047159 BC067280 BC101526 AAI01527 BC101528 AAI01529 BF026507 BQ434462 DA253448 DA330657 XM_005248933 XP_005248990 XM_005248934 XP_005248991 XM_005248935 XP_005248992 XM_005248936 XP_005248993 XM_005248937 XP_005248994 XM_006715021 XP_006715084 XM_011514390 XP_011512692 XM_011514391 XP_011512693 XM_011514392 XP_011512694 NM_001242648 NP_001229577 NM_030948 NP_112210
Function	Binds actin monomers (G actin) and plays a role in the reorganization of the actin cytoskeleton and in formation of actin stress fibers. Plays a role in cell motility. Plays a role in the formation of tubules by endothelial cells. Regulates PPP1CA activity. Required for normal cell survival. {ECO:0000269|PubMed:21798305, ECO:0000269|PubMed:21939755}.
Subcellular Location	Cytoplasm {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Nucleus {ECO:0000250}. Note=Enriched at synapses (By similarity). Cytoplasmic in resting cells, and is imported into the nucleus upon serum stimulation. Interaction with actin prevents nuclear import (By similarity). {ECO:0000250}.
Tissue Specificity	Detected in umbilical vein endothelial cells. {ECO:0000269|PubMed:21939755}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

Human PHACTR1 full length protein - ab165977 from Abcam Category Protein Source Wheat germ Species Human

PHACTR1 Antibody Blocking Peptide - LS-E20010 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PHACTR1 Protein - H00221692-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

PHACTR1 Blocking Peptide - 33R-7717 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PHACTR1 - H00221692-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

PHACTR1 fusion protein - ag20125 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human PHACTR1 - PHACTR1-901H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Human Phosphatase and actin regulator 1(PHACTR1) - CSB-YP017880HU CSB-EP017880HU CSB-BP017880HU CSB-MP017880HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Phosphatase and actin regulator 1 (PHACTR1), Recombinant Protein - MBS1287807 from MyBioSource Category Protein Prices $1,380.00, $1,380.00, $1,600.00, $1,600.00, $2,300.00, $2,300.00, $2,740.00, $2,740.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

PHACTR1 Protein - NBP1-85186PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

PHACTR1 Recombinant Protein Antigen - NBP1-85185PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

PHACTR1 Recombinant Protein Antigen - NBP1-84232PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

PHACTR1 Peptide, Human - M34GP11673H from Creative Peptides Category Peptide Source Synthetic. Species Human

Search more