Gene Symbol | TTK |
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Entrez Gene | 7272 |
Alt Symbol | CT96, ESK, MPH1, MPS1, MPS1L1, PYT |
Species | Human |
Gene Type | protein-coding |
Description | TTK protein kinase |
Other Description | cancer/testis antigen 96|dual specificity protein kinase TTK|monopolar spindle 1 kinase|monopolar spindle 1-like 1|phosphotyrosine picked threonine kinase|phosphotyrosine picked threonine-protein kinase |
Swissprots | Q5TCS0 Q15272 Q9NTM0 P33981 B2RDW2 E1P543 Q9BW51 A8K8U5 |
Accessions | CAV33297 CCO75436 CCO75438 CCQ77693 CCQ77702 CCQ77711 CCQ77720 CDH48199 CDH61621 CDH61675 CDH61694 CDH88992 CDH92530 CDH92544 CDH92555 CDH92802 CDH92899 CDI44674 CDI44683 EAW48699 EAW48700 P33981 AK095599 AK292460 BAF85149 AK315696 BAG38059 AU154042 AX775733 CAE11566 BC000633 AAH00633 BC032858 AAH32858 DA853919 DQ891960 ABM82886 DQ895150 ABM86076 X70500 CAA49912 XM_011536099 XP_011534401 XM_011536100 XP_011534402 NM_001166691 NP_001160163 NM_003318 NP_003309 |
Function | Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint. {ECO:0000269|PubMed:18243099}. |
Tissue Specificity | Present in rapidly proliferating cell lines. |
Top Pathways | Cell cycle |
Active human Mps1 full length protein - ab89589 from Abcam
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Human Mps1 protein fragment - ab159755 from Abcam
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TTK Recombinant Protein - H00007272-P01 from Novus Biologicals
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TTK Partial Recombinant Protein - H00007272-Q01 from Novus Biologicals
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Recombinant Human TTK Protein - P4790 from Novus Biologicals
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TTK Peptide - P3108 from Novus Biologicals
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TTK-Antibody-N-term-Blocking-Peptide - BP17197a from Abgent, a WuXi AppTec company
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TTK-MPS1-Antibody-N-term-Blocking-peptide - BP8103a from Abgent, a WuXi AppTec company
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TTK - H00007272-P01-10 from Acris Antibodies
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TTK - H00007272-P01-25 from Acris Antibodies
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TTK - H00007272-Q01-10 from Acris Antibodies
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TTK - H00007272-Q01-25 from Acris Antibodies
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TTK - P4790 from Acris Antibodies
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TTK - P5808 from Acris Antibodies
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TTK fusion protein - ag0405 from Proteintech Group
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Recombinant Human TTK, GST-tagged, Active - TTK-452H from Creative Biomart
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Recombinant Human TTK Protein Kinase, GST-His - TTK-748H from Creative Biomart
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Recombinant Human TTK - TTK-29701TH from Creative Biomart
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Recombinant Human TTK (Active), GST-tagged - TTK-1503H from Creative Biomart
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Recombinant TTK Protein Kinase (TTK) - RPG991Hu01 from Uscn Life Science Inc.
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Recombinant TTK Protein Kinase (TTK) - RPG991Mu01 from Uscn Life Science Inc.
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Recombinant TTK Protein Kinase (TTK) - RPG991Ra01 from Uscn Life Science Inc.
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Recombinant Human Dual specificity protein kinase TTK(TTK) ,partial - CSB-YP025251HU CSB-EP025251HU CSB-BP025251HU CSB-MP025251HU from Cusabio
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TTK - TP300093 from Acris Antibodies
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Recombinant Human TTK Active GST-His - CRT015 from Cell Science
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