TTK

Gene Symbol	TTK
Entrez Gene	7272
Alt Symbol	CT96, ESK, MPH1, MPS1, MPS1L1, PYT
Species	Human
Gene Type	protein-coding
Description	TTK protein kinase
Other Description	cancer/testis antigen 96|dual specificity protein kinase TTK|monopolar spindle 1 kinase|monopolar spindle 1-like 1|phosphotyrosine picked threonine kinase|phosphotyrosine picked threonine-protein kinase
Swissprots	Q5TCS0 Q15272 Q9NTM0 P33981 B2RDW2 E1P543 Q9BW51 A8K8U5
Accessions	CAV33297 CCO75436 CCO75438 CCQ77693 CCQ77702 CCQ77711 CCQ77720 CDH48199 CDH61621 CDH61675 CDH61694 CDH88992 CDH92530 CDH92544 CDH92555 CDH92802 CDH92899 CDI44674 CDI44683 EAW48699 EAW48700 P33981 AK095599 AK292460 BAF85149 AK315696 BAG38059 AU154042 AX775733 CAE11566 BC000633 AAH00633 BC032858 AAH32858 DA853919 DQ891960 ABM82886 DQ895150 ABM86076 X70500 CAA49912 XM_011536099 XP_011534401 XM_011536100 XP_011534402 NM_001166691 NP_001160163 NM_003318 NP_003309
Function	Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint. {ECO:0000269|PubMed:18243099}.
Tissue Specificity	Present in rapidly proliferating cell lines.
Top Pathways	Cell cycle

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SignalSilence ® TTK siRNA I - 6367 from Cell Signaling Technology Category siRNA

SignalSilence ® TTK siRNA II - 6368 from Cell Signaling Technology Category siRNA

TTK CRISPR/Cas9 KO Plasmid (h) - sc-417754 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

TTK HDR Plasmid (h) - sc-417754-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

TTK Double Nickase Plasmid (h) - sc-417754-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

TTK Double Nickase Plasmid (h2) - sc-417754-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

TTK CRISPR Activation Plasmid (h) - sc-417754-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

TTK CRISPR Activation Plasmid (h2) - sc-417754-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

TTK Lentiviral Activation Particles (h) - sc-417754-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

TTK Lentiviral Activation Particles (h2) - sc-417754-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

TTK siRNA (h) - sc-36758 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

TTK shRNA Plasmid (h) - sc-36758-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

TTK shRNA (h) Lentiviral Particles - sc-36758-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

TTK RNAi - H00007272-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU026581 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

MISSION® siRNA - SIHK2380 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK2379 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK2378 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN1527 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1527 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

TTK siRNA (Human) - CRH4970 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

TTK - MBS829007 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

TTK - MBS826831 from MyBioSource Prices $255.00 Sizes 5 od Species Reactivities Human

shRNA set against Human TTK (NM_003318.4) - SHH437304 from Creative biogene Category siRNA Species Reactivities Human

TTK siRNA - orb219189 from Biorbyt Category siRNA Prices $417.00 Sizes 5 od (260 nm) Species Reactivities Human

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