TTK

Gene Symbol TTK
Entrez Gene 7272
Alt Symbol CT96, ESK, MPH1, MPS1, MPS1L1, PYT
Species Human
Gene Type protein-coding
Description TTK protein kinase
Other Description cancer/testis antigen 96|dual specificity protein kinase TTK|monopolar spindle 1 kinase|monopolar spindle 1-like 1|phosphotyrosine picked threonine kinase|phosphotyrosine picked threonine-protein kinase
Swissprots Q5TCS0 Q15272 Q9NTM0 P33981 B2RDW2 E1P543 Q9BW51 A8K8U5
Accessions CAV33297 CCO75436 CCO75438 CCQ77693 CCQ77702 CCQ77711 CCQ77720 CDH48199 CDH61621 CDH61675 CDH61694 CDH88992 CDH92530 CDH92544 CDH92555 CDH92802 CDH92899 CDI44674 CDI44683 EAW48699 EAW48700 P33981 AK095599 AK292460 BAF85149 AK315696 BAG38059 AU154042 AX775733 CAE11566 BC000633 AAH00633 BC032858 AAH32858 DA853919 DQ891960 ABM82886 DQ895150 ABM86076 X70500 CAA49912 XM_011536099 XP_011534401 XM_011536100 XP_011534402 NM_001166691 NP_001160163 NM_003318 NP_003309
Function Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint. {ECO:0000269|PubMed:18243099}.
Tissue Specificity Present in rapidly proliferating cell lines.
Top Pathways Cell cycle

TTK (D15B7) Rabbit mAb - 5469 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D15B7
Western blot analysis of extracts from UT7, Ramos, and HEL cells using TTK (D15B7) Rabbit mAb.

TTK Antibody - 3255 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of recombinant GST-TTK (#7655) and extracts from OVCAR8 and K562 cell lines using TTK Antibody.

TTK (D-8) - sc-376842 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TTK (D-8): sc-376842. Western blot analysis of TTK expression in C32 (A) and BJAB (B) whole cell lysates.

TTK (F-16) - sc-32017 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TTK (F-16): sc-32017. Western blot analysis of TTK expression in MCF7 (A), BJAB (B), U-2 OS (C), HeLa (D) and Ramos (E) whole cell lysates and HeLa nuclear extract (F).

TTK (N1) - sc-56968 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TTK (N1): sc-56968. Western blot analysis of TTK expression in U-2 OS (A), HeLa (B) and BJAB (C) whole cell lysates.

TTK (C-19) - sc-540 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TTK (C-19): sc-540. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic and nuclear staining.

TTK (H-130) - sc-25420 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

TTK (N-18) - sc-32015 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Mps1 antibody - ab187520 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Mps1 antibody (ab187520) at 1/500 dilutionLane 1 : U251 cell extractsLane 2 : Mouse testis cell extractsLane 3 : Mouse spleen cell extracts

Anti-Mps1 antibody - ab24227 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Mps1 antibody (ab24227)Lane 1 : HeLa cell lyste at 15µg and ab at 0.033ug/mlLane 2 : HeLa cell lyste at 50ug and ab at 0.033ug/mlLane 3 : HeLa cell lyste at 50ug and ab at 0.33ug/mlLane 4 : HeLa cell lyste at 50ug and ab at 0.33ug/mlLane 5 : HeLa cell lyste at 2mg and ab at 1ug/2mg lysateLane 6 : HeLa cell lyste at 2mg and ab at 1ug/2mg lysateLane 7 : HeLa cell lyste at 2mg and ab at 1ug/2mg lysatedeveloped using the ECL technique

Anti-Mps1 antibody - ab24226 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
developed using the ECL technique

Anti-Mps1 antibody - ab167654 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-Mps1 antibody (ab167654) at 1 µg/mlLane 1 : Mps1 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG HRP at 1/2500 dilution

Anti-Mps1 antibody - ab130625 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Mps1 antibody (ab130625) at 1/100 dilution + SK-BR-3 cell line lysates at 35 µg

Anti-Mps1 antibody [N1] - ab11108 from Abcam

Prices $401.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone N1
All lanes : Anti-Mps1 antibody [N1] (ab11108) at 1 µg/mlLane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate Lane 2 : HeLa (Human epithelial carcinoma cell line) Nuclear Lysate Lane 3 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell Lysate Lane 4 : Jurkat (Human T cell lymphoblast-like cell line) Nuclear Lysate (ab14844)Lysates/proteins at 20 µg per lane.SecondaryGoat polyclonal to Mouse IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Mps1 antibody - N-terminal - ab135819 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Mps1 antibody - N-terminal (ab135819) at 1/100 dilution + 293 cell line lysates at 35 µg

Anti-MPS1 / TTK Antibody (N-Terminus) - LS-C25659 from LifeSpan Bioscience

Prices $495.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal

Anti-MPS1 / TTK Antibody - LS-C89831 from LifeSpan Bioscience

Prices $575.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MPS1 / TTK Antibody (C-Terminus) - LS-C25658 from LifeSpan Bioscience

Prices $455.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal

Anti-MPS1 / TTK Antibody - LS-C89832 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MPS1 / TTK Antibody - LS-C124719 from LifeSpan Bioscience

Prices $435.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

Anti-MPS1 / TTK Antibody (aa281-481) - LS-C132717 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-MPS1 / TTK Antibody (clone GF1) - LS-C190306 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone GF1

Anti-MPS1 / TTK Antibody (clone GF1) - LS-C190305 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone GF1

Anti-MPS1 / TTK Antibody (aa6-35, AP) - LS-C224529 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MPS1 / TTK Antibody (aa6-35, APC) - LS-C224530 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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