Gene Symbol | MED26 |
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Entrez Gene | 9441 |
Alt Symbol | CRSP7, CRSP70 |
Species | Human |
Gene Type | protein-coding |
Description | mediator complex subunit 26 |
Other Description | ARC70|CRSP complex subunit 7|activator-recruited cofactor 70 kDa component|cofactor required for Sp1 transcriptional activation subunit 7|cofactor required for Sp1 transcriptional activation, subunit 7 (70kD)|cofactor required for Sp1 transcriptional activation, subunit 7, 70kDa|mediator of RNA polymerase II transcription subunit 26|transcriptional coactivator CRSP70 |
Swissprots | Q0VGB6 A1A4S3 O95402 |
Accessions | EAW84554 O95402 AF104253 AAD12722 AK128435 AK313778 BAG36516 BC047040 BC063628 BC105951 BC105952 BC105953 BC110430 AAI10431 BC127214 BC127215 AAI27216 BC143047 NM_004831 NP_004822 |
Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
Subcellular Location | Nucleus {ECO:0000305}. |
MED26 Antibody - 13641 from Cell Signaling Technology
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CRSP70 (E-11) - sc-137230 from Santa Cruz Biotechnology
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CRSP70 (C-19) - sc-9425 from Santa Cruz Biotechnology
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CRSP70 (F-5) - sc-137196 from Santa Cruz Biotechnology
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CRSP70 (G-11) - sc-166614 from Santa Cruz Biotechnology
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CRSP70 (H-228) - sc-48776 from Santa Cruz Biotechnology
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CRSP70 (T-20) - sc-9426 from Santa Cruz Biotechnology
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Anti-CRSP7 antibody - ab77036 from Abcam
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Anti-CRSP7 antibody - ab65112 from Abcam
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Anti-CRSP7 antibody - ab114092 from Abcam
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Anti-CRSP7 antibody [2216C1a] - ab50619 from Abcam
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Anti-MED26 / CRSP7 Antibody - LS-C79471 from LifeSpan Bioscience
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Anti-MED26 / CRSP7 Antibody (aa190-220, AP) - LS-C237524 from LifeSpan Bioscience
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Anti-MED26 / CRSP7 Antibody (aa190-220, APC) - LS-C237525 from LifeSpan Bioscience
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Anti-MED26 / CRSP7 Antibody (clone 2216C1a) - LS-C184435 from LifeSpan Bioscience
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Anti-MED26 / CRSP7 Antibody (aa190-220, Biotin) - LS-C237526 from LifeSpan Bioscience
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Anti-MED26 / CRSP7 Antibody (aa190-220, FITC) - LS-C237527 from LifeSpan Bioscience
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Anti-MED26 / CRSP7 Antibody (aa190-220, PE) - LS-C237530 from LifeSpan Bioscience
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Anti-MED26 / CRSP7 Antibody (aa190-220, Azide-free, HRP) - LS-C248793 from LifeSpan Bioscience
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Anti-MED26 / CRSP7 Antibody (aa36-85) - LS-C109826 from LifeSpan Bioscience
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Anti-MED26 / CRSP7 Antibody (N-Terminus) - LS-C110282 from LifeSpan Bioscience
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Anti-MED26 / CRSP7 Antibody (aa1-50) - LS-C289122 from LifeSpan Bioscience
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Anti-MED26 / CRSP7 Antibody - LS-C311375 from LifeSpan Bioscience
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Anti-MED26 / CRSP7 Antibody (aa543-593) - LS-C289120 from LifeSpan Bioscience
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Anti-MED26 / CRSP7 Antibody (aa190-220) - LS-C322941 from LifeSpan Bioscience
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