| Gene Symbol |
MED26
|
| Entrez Gene |
9441
|
| Alt Symbol |
CRSP7, CRSP70
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
mediator complex subunit 26
|
| Other Description |
ARC70|CRSP complex subunit 7|activator-recruited cofactor 70 kDa component|cofactor required for Sp1 transcriptional activation subunit 7|cofactor required for Sp1 transcriptional activation, subunit 7 (70kD)|cofactor required for Sp1 transcriptional activation, subunit 7, 70kDa|mediator of RNA polymerase II transcription subunit 26|transcriptional coactivator CRSP70
|
| Swissprots |
Q0VGB6 A1A4S3 O95402
|
| Accessions |
EAW84554 O95402 AF104253 AAD12722 AK128435 AK313778 BAG36516 BC047040 BC063628 BC105951 BC105952 BC105953 BC110430 AAI10431 BC127214 BC127215 AAI27216 BC143047 NM_004831 NP_004822
|
| Function |
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
|
| Subcellular Location |
Nucleus {ECO:0000305}.
|