Gene Symbol | MED26 |
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Entrez Gene | 9441 |
Alt Symbol | CRSP7, CRSP70 |
Species | Human |
Gene Type | protein-coding |
Description | mediator complex subunit 26 |
Other Description | ARC70|CRSP complex subunit 7|activator-recruited cofactor 70 kDa component|cofactor required for Sp1 transcriptional activation subunit 7|cofactor required for Sp1 transcriptional activation, subunit 7 (70kD)|cofactor required for Sp1 transcriptional activation, subunit 7, 70kDa|mediator of RNA polymerase II transcription subunit 26|transcriptional coactivator CRSP70 |
Swissprots | Q0VGB6 A1A4S3 O95402 |
Accessions | EAW84554 O95402 AF104253 AAD12722 AK128435 AK313778 BAG36516 BC047040 BC063628 BC105951 BC105952 BC105953 BC110430 AAI10431 BC127214 BC127215 AAI27216 BC143047 NM_004831 NP_004822 |
Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
Subcellular Location | Nucleus {ECO:0000305}. |
Human CRSP7 full length protein - ab160489 from Abcam
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Human CRSP7 protein fragment - ab160490 from Abcam
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MED26 / CRSP7 Antibody Blocking Peptide - LS-E4167 from LifeSpan Bioscience
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MED26 / CRSP7 Antibody Blocking Peptide - LS-E11934 from LifeSpan Bioscience
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MED26 / CRSP7 Antibody Blocking Peptide - LS-E13851 from LifeSpan Bioscience
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Recombinant Human MED26 Protein - H00009441-Q01 from Novus Biologicals
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Recombinant Human MED26 Protein - H00009441-P01 from Novus Biologicals
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MED26-Antibody-Center-Blocking-Peptide - BP16422c from Abgent, a WuXi AppTec company
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CRSP7 Blocking Peptide - abx063587 from Abbexa
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MED26 - H00009441-P01-10 from Acris Antibodies
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MED26 - H00009441-P01-25 from Acris Antibodies
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MED26 - H00009441-Q01-10 from Acris Antibodies
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MED26 - H00009441-Q01-25 from Acris Antibodies
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MED26 fusion protein - ag15381 from Proteintech Group
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MED26 fusion protein - Ag16915 from Proteintech Group
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CRSP7 Blocking Peptide - CBP2393 from Cohesion Biosciences
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CRSP70 (S7) Peptide - BS1902P from Bioworld Technology
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Recombinant Human Mediator of RNA polymerase II transcription subunit 26(MED26) - CSB-YP013659HU CSB-EP013659HU CSB-BP013659HU CSB-MP013659HU from Cusabio
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MED26 Protein - NBP1-92104PEP from Novus Biologicals
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MED26 Peptide, Human - M34GP09371H from Creative Peptides
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MED26 Recombinant Protein Antigen - NBP2-57785PEP from Novus Biologicals
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Mediator of RNA polymerase II transcription subunit 26 (MED26), Recombinant Protein - MBS1030321 from MyBioSource
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