CDC42SE2

Gene Symbol	CDC42SE2
Entrez Gene	56990
Alt Symbol	SPEC2
Species	Human
Gene Type	protein-coding
Description	CDC42 small effector 2
Other Description	CDC42 small effector protein 2|non-kinase Cdc42 effector protein SPEC2|small effector of CDC42 protein 2
Swissprots	Q9NRR3 Q4KMT9 B2R622
Accessions	EAW62372 EAW62373 Q9NRR3 AF131831 AF189692 AAF87598 AI440226 AK025620 AK312406 BAG35319 BC023555 BC050430 BC058909 BC096703 AAH96703 BC096738 AAH96738 BC098349 AAH98349 BI460220 BI522591 CB135092 DA321488 NM_001038702 NP_001033791 NM_020240 NP_064625
Function	Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages. {ECO:0000269|PubMed:10816584, ECO:0000269|PubMed:15840583}.
Subcellular Location	Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor. Cell projection, phagocytic cup. Note=Recruited to the activated TCR prior actin polymerization. Localizes at the phagocytic cup of macrophages.
Tissue Specificity	Widely expressed. Expressed at higher level in T-lymphocytes. Highly expressed in CCRF-CEM T-lymphocytes, Jurkat T-lymphocytes, and Raji B-lymphocytes compared (at protein level). {ECO:0000269|PubMed:15840583}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CDC42SE2 protein fragment - ab163453 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

CDC42SE2 Antibody Blocking Peptide - LS-E24419 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CDC42SE2 Partial Recombinant Protein - H00056990-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

CDC42SE2-Antibody-N-term-Blocking-Peptide - BP16223a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CDC42SE2 - H00056990-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CDC42SE2 - H00056990-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CDC42SE2 fusion protein - ag16011 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

CDC42SE2 fusion protein - Ag17015 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human CDC42 small effector protein 2(CDC42SE2) - CSB-YP882090HU CSB-EP882090HU CSB-BP882090HU CSB-MP882090HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

CDC42SE2 (full length, N-term HIS tag) - TP760245 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

CDC42SE2 (full length, N-term HIS tag, transcript variant 2) - TP760861 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

CDC42 small effector protein 2 (CDC42SE2), Recombinant Protein - MBS1384428 from MyBioSource Category Protein Prices $815.00, $815.00, $1,040.00, $1,040.00, $1,155.00, $1,155.00, $1,610.00, $1,610.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

CDC42SE2 Recombinant Protein Antigen - NBP1-82131PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

CDC42SE2 Peptide, Human - M34GP02815H from Creative Peptides Category Peptide Source Synthetic. Species Human

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