CDC42SE2

Gene Symbol CDC42SE2
Entrez Gene 56990
Alt Symbol SPEC2
Species Human
Gene Type protein-coding
Description CDC42 small effector 2
Other Description CDC42 small effector protein 2|non-kinase Cdc42 effector protein SPEC2|small effector of CDC42 protein 2
Swissprots Q9NRR3 Q4KMT9 B2R622
Accessions EAW62372 EAW62373 Q9NRR3 AF131831 AF189692 AAF87598 AI440226 AK025620 AK312406 BAG35319 BC023555 BC050430 BC058909 BC096703 AAH96703 BC096738 AAH96738 BC098349 AAH98349 BI460220 BI522591 CB135092 DA321488 NM_001038702 NP_001033791 NM_020240 NP_064625
Function Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages. {ECO:0000269|PubMed:10816584, ECO:0000269|PubMed:15840583}.
Subcellular Location Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor. Cell projection, phagocytic cup. Note=Recruited to the activated TCR prior actin polymerization. Localizes at the phagocytic cup of macrophages.
Tissue Specificity Widely expressed. Expressed at higher level in T-lymphocytes. Highly expressed in CCRF-CEM T-lymphocytes, Jurkat T-lymphocytes, and Raji B-lymphocytes compared (at protein level). {ECO:0000269|PubMed:15840583}.

Anti-CDC42SE2 antibody - ab122492 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CDC42SE2 antibody (ab122492) at 1/250 dilutionLane 1 : RT 4 cell lysateLane 2 : U 251 MG cell lysateLane 3 : Human Plasma lysateLane 4 : Human Liver lysateLane 5 : Human Tonsil lysatedeveloped using the ECL technique

Anti-CDC42SE2 Antibody (clone 1B2) - LS-C340452 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1B2
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDC42SE2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDC42SE2 (1:2000).

Anti-CDC42SE2 Antibody (clone 2C5) - LS-C340454 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2C5
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDC42SE2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDC42SE2 (1:2000).

Anti-CDC42SE2 Antibody (clone 10A5) - LS-C340455 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 10A5
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDC42SE2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDC42SE2 (1:2000).

Anti-CDC42SE2 Antibody (C-Terminus) - LS-C169958 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

CDC42SE2 Antibody - NBP1-82131 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CDC42SE2 Antibody [NBP1-82131] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).

CDC42SE2 Antibody - H00056990-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Anti-CDC42SE2 antibody produced in rabbit - HPA038624 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CDC42SE2: <B>Cat. No. HPA038624</B>: Immunohistochemical staining of human small intestine shows strong cytoplasmic and membranous positivity in glandular cells.

CDC42SE2 Antibody - middle region (ARP67446_P050) - ARP67446_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CDC42SE2 antibody - 21424-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human colon tissue slide using 21424-1-AP( CDC42SE2 Antibody) at dilution of 1:50 (under 10x lens)

CDC42SE2 antibody - H00056990-A01 from Acris Antibodies

Prices $300.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

CDC42SE2 antibody - 21424-1-AP from Proteintech Group

Prices $279.00
Sizes con: 36 μg/150μl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human colon tissue slide using 21424-1-AP( CDC42SE2 Antibody) at dilution of 1:50 (under 10x lens)

Anti-CDC42SE2 (aa 1-84) polyclonal antibody - DPAB-DC2549 from Creative Diagnostics

Host Mouse
Clonality Polyclonal

Rabbit anti-Human CDC42SE2 polyclonal antibody - DPABH-01977 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

Anti-CDC42SE2 (aa 31-84) polyclonal antibody - DPABH-20793 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

CDC42SE2 antibody - TA808192 from Acris Antibodies

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone OTI1B12
Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-CDC42SE2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA808192)(1:150)

CDC42SE2 antibody - TA808181 from Acris Antibodies

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone OTI1B2
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDC42SE2 (RC212101, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDC42SE2.(1:2000)

CDC42SE2 antibody - TA808193 from Acris Antibodies

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone OTI2C5
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDC42SE2 (RC212101, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDC42SE2.(1:2000)

CDC42SE2 antibody - TA808200 from Acris Antibodies

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone OTI10A5
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDC42SE2 (RC212101, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDC42SE2.(1:2000)

CDC42SE2 antibody - TA808229 from Acris Antibodies

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone OTI11F7
Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-CDC42SE2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA808229)(1:150)

CDC42SE2 Antibody (1B12) - NBP2-46191 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1B12
Western Blot: CDC42SE2 Antibody (1B12) [NBP2-46191] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDC42SE2.

CDC42SE2 antibody - TA331833 from Acris Antibodies

Prices $325.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Host: Rabbit; Target Name: CDC42SE2; Sample Tissue: COLO205 Whole Cell lysates; Antibody Dilution: 1.0ug/ml

anti-CDC42SE2 antibody - A001533 from Biobool

Host Rabbit
Clonality Polyclonal

Anti-CDC42SE2 Antibody A12132 - A12132 from Boster Bio

Prices $299.00
Sizes 1
Host Rabbit
Clonality Polyclonal

CDC42SE2, Polyclonal Antibody - MBS767765 from MyBioSource

Prices $265.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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