NLRX1

Gene Symbol NLRX1
Entrez Gene 79671
Alt Symbol CLR11.3, DLNB26, NOD26, NOD5, NOD9
Species Human
Gene Type protein-coding
Description NLR family member X1
Other Description NLR family, X1|NOD-like receptor X1|caterpiller protein 11.3|nucleotide-binding oligomerization domain protein 26|nucleotide-binding oligomerization domain protein 5|nucleotide-binding oligomerization domain protein 9|nucleotide-binding oligomerization domain, leucine rich repeat containing X1
Swissprots B3KPK2 A8K6Q1 Q96D51 Q7RTR3 Q9H724 Q86UT6 B3KTA2
Accessions EAW67467 EAW67468 EAW67469 Q86UT6 AB094095 BAC76049 AK025131 BAB15075 AK056454 BAG51714 AK095247 BAG53014 AK225223 AK291716 BAF84405 AK303002 BAH13875 AL049456 CAH56420 AY245437 AAP31240 BC013199 AAH13199 BC023974 BC110890 AAI10891 BK001111 DAA01244 BX647705 DA107044 DA441499 EF452237 ABO40480 XM_005271669 XP_005271726 XM_005271670 XP_005271727 XM_005271671 XP_005271728 XM_005271672 XP_005271729 XM_006718904 XP_006718967 XM_011542980 XP_011541282 NM_001282143 NP_001269072 NM_001282144 NP_001269073 NM_001282358 NP_001269287 NM_024618 NP_078894 NM_170722
Function Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (PubMed:18200010). Has no inhibitory function on NF- Kappa-B and type 1 interferon signaling pathways, but enhances NF- Kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species (PubMed:18219313). {ECO:0000269|PubMed:18200010, ECO:0000269|PubMed:18219313}.
Subcellular Location Mitochondrion outer membrane {ECO:0000269|PubMed:18200010, ECO:0000269|PubMed:18219313}.
Tissue Specificity Ubiquitously expressed. Strongest expression in mammary gland, heart and muscle. Detected in HeLa, HEK293T, THP-1, HL-60, Raji and Jurkat cell lines (at protein level). {ECO:0000269|PubMed:15952891, ECO:0000269|PubMed:18200010, ECO:0000269|PubMed:18219313}.
Top Pathways RIG-I-like receptor signaling pathway, Influenza A

NLR family member X1 (NLRX1), Human, ELISA Kit - CSB-EL015878HU from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

NLR family member X1, ELISA Kit - MBS943380 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity The minimum detectable dose of human NLRX1 is typically less than 6.25 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
Range 25 pg/ml-1600 pg/ml.

NOD-like receptor9 (NLR), ELISA Kit - MBS265751 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

NOD-like receptor9 (NLR), ELISA Kit - MBS2600237 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

NOD-like receptor9 (NLR), ELISA Kit - MBS266542 from MyBioSource

Category ELISA Kit
Prices $290.00, $450.00, $1,755.00, $3,150.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

NOD-like receptor9 (NLR), ELISA Kit - MBS265784 from MyBioSource

Category ELISA Kit
Prices $290.00, $450.00, $1,755.00, $3,150.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

NOD-like receptor9 (NLR), ELISA Kit - MBS267330 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

NOD-like receptor9 (NLR), ELISA Kit - MBS265917 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

NOD-like receptor9 (NLR), ELISA Kit - MBS266691 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

NOD-like receptor9 (NLR), ELISA Kit - MBS264407 from MyBioSource

Category ELISA Kit
Prices $275.00, $420.00, $1,615.00, $2,880.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human NLR family member X1(NLRX1) ELISA kit - CSB-EL015878HU from Cusabio

Category ELISA Kit
Sensitivity 6.25 pg/ml.
Range 25 pg/ml-1600 pg/ml

Human NLR family member X1 (NLRX1) ELISA Kit - EKC34830 from Biomatik

Category ELISA Kit
Prices $705.00, $2,820.00, $5,288.00
Sizes 96 t, 5x96t, 10x96t
Sensitivity 6.25 pg/ml
Range 25 pg/ml-1600 pg/ml

Human NLRX1 ELISA Kit - E026659 from Biobool

Category ELISA Kit
Sensitivity The minimum detectable dose of human NLRX1 is typically less than 6.25 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the me

anti-NLRX1 / NOD9 antibody - ARG65314 from Arigo Biolaboratories

Category ELISA Kit

NLRX1 ELISA Kit (Human) (OKCA01393) - OKCA01393 from Aviva Systems Biology

Category ELISA Kit
Prices $600.00
Sizes 96 wells
Sensitivity 6.25 pg/mL
Range 25 - 1,600 pg/mL

NOD-like receptor9 (NLR), ELISA Kit - MBS2609565 from MyBioSource

Category ELISA Kit
Prices $300.00, $475.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

NOD-like receptor9, ELISA Kit - MBS2606774 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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