Gene Symbol |
PCSK1
|
Entrez Gene |
5122
|
Alt Symbol |
BMIQ12, NEC1, PC1, PC3, SPC3
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
proprotein convertase subtilisin/kexin type 1
|
Other Description |
neuroendocrine convertase 1|prohormone convertase 1|prohormone convertase 3
|
Swissprots |
P78478 B7Z8T7 Q92532 E9PHA1 P29120
|
Accessions |
AAA73788 BAA11133 EAW96062 EAW96063 P29120 AB208874 BAD92111 AK303888 BAH14073 AK308575 BC031211 BC130295 AAI30296 BC136486 AAI36487 DA192592 M90753 AAA59918 X64810 CAA46031 NM_000439 NP_000430 NM_001177875 NP_001171346 NM_001177876
|
Function |
Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin and insulin.
|
Subcellular Location |
Cytoplasmic vesicle, secretory vesicle. Note=Localized in the secretion granules.
|