Gene Symbol | PCSK1 |
---|---|
Entrez Gene | 5122 |
Alt Symbol | BMIQ12, NEC1, PC1, PC3, SPC3 |
Species | Human |
Gene Type | protein-coding |
Description | proprotein convertase subtilisin/kexin type 1 |
Other Description | neuroendocrine convertase 1|prohormone convertase 1|prohormone convertase 3 |
Swissprots | P78478 B7Z8T7 Q92532 E9PHA1 P29120 |
Accessions | AAA73788 BAA11133 EAW96062 EAW96063 P29120 AB208874 BAD92111 AK303888 BAH14073 AK308575 BC031211 BC130295 AAI30296 BC136486 AAI36487 DA192592 M90753 AAA59918 X64810 CAA46031 NM_000439 NP_000430 NM_001177875 NP_001171346 NM_001177876 |
Function | Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin and insulin. |
Subcellular Location | Cytoplasmic vesicle, secretory vesicle. Note=Localized in the secretion granules. |