| Gene Symbol |
FRS3
|
| Entrez Gene |
10817
|
| Alt Symbol |
FRS2-beta, FRS2B, FRS2beta, SNT-2, SNT2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
fibroblast growth factor receptor substrate 3
|
| Other Description |
FGFR substrate 3|FGFR-signaling adaptor SNT2|suc1-associated neurotrophic factor target 2 (FGFR signalling adaptor)
|
| Swissprots |
O43559 Q5T3D5
|
| Accessions |
EAX04060 O43559 AF036718 AAB92555 BC010611 AAH10611 BM741175 CR457026 CAG33307 DQ892075 ABM83001 DQ895268 ABM86194 HY036161 XM_011514254 XP_011512556 XM_011514255 XP_011512557 NM_006653 NP_006644
|
| Function |
Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2. {ECO:0000269|PubMed:15094036}.
|
| Subcellular Location |
Membrane; Lipid-anchor.
|
