| Gene Symbol | FRS3 |
|---|---|
| Entrez Gene | 10817 |
| Alt Symbol | FRS2-beta, FRS2B, FRS2beta, SNT-2, SNT2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | fibroblast growth factor receptor substrate 3 |
| Other Description | FGFR substrate 3|FGFR-signaling adaptor SNT2|suc1-associated neurotrophic factor target 2 (FGFR signalling adaptor) |
| Swissprots | O43559 Q5T3D5 |
| Accessions | EAX04060 O43559 AF036718 AAB92555 BC010611 AAH10611 BM741175 CR457026 CAG33307 DQ892075 ABM83001 DQ895268 ABM86194 HY036161 XM_011514254 XP_011512556 XM_011514255 XP_011512557 NM_006653 NP_006644 |
| Function | Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2. {ECO:0000269|PubMed:15094036}. |
| Subcellular Location | Membrane; Lipid-anchor. |
FRS3 - MBS1278673 from MyBioSource
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Human FRS3 cDNA clone(NM_006653.3) - CDFH007131 from Creative Biomart
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Human FRS3 cDNA clone(NM_006653.3) - CDFH007132 from Creative Biomart
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Human FRS3 ORF Clone(NM_006653.3) - CDCR293229 from Creative Biomart
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Human FRS3 ORF Clone(NM_006653.3) - CDCR293230 from Creative Biomart
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Human FRS3 ORF Clone(NM_006653.3) - CDCL164015 from Creative Biomart
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Human FRS3 ORF clone - CDCL109569 from Creative Biomart
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Human FRS3 ORF clone - CDCL109570 from Creative Biomart
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Human FRS3 ORF Clone(NM_006653.3) - CDCR293229 from Creative biogene
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Human FRS3 ORF Clone (BC010611) - CDCS412846 from Creative biogene
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Human FRS3 cDNA Clone(NM_006653.3) - CDFH007131 from Creative biogene
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Human FRS3 cDNA Clone(NM_006653.3) - CDFH007132 from Creative biogene
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