Gene Symbol | FRS3 |
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Entrez Gene | 10817 |
Alt Symbol | FRS2-beta, FRS2B, FRS2beta, SNT-2, SNT2 |
Species | Human |
Gene Type | protein-coding |
Description | fibroblast growth factor receptor substrate 3 |
Other Description | FGFR substrate 3|FGFR-signaling adaptor SNT2|suc1-associated neurotrophic factor target 2 (FGFR signalling adaptor) |
Swissprots | O43559 Q5T3D5 |
Accessions | EAX04060 O43559 AF036718 AAB92555 BC010611 AAH10611 BM741175 CR457026 CAG33307 DQ892075 ABM83001 DQ895268 ABM86194 HY036161 XM_011514254 XP_011512556 XM_011514255 XP_011512557 NM_006653 NP_006644 |
Function | Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2. {ECO:0000269|PubMed:15094036}. |
Subcellular Location | Membrane; Lipid-anchor. |
FRS3 (T-19) - sc-161606 from Santa Cruz Biotechnology
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Anti-SNT2 antibody - ab89809 from Abcam
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Anti-SNT2 antibody - ab90030 from Abcam
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Anti-SNT2 antibody - ab199612 from Abcam
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Anti-SNT2 antibody - ab133880 from Abcam
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Anti-SNT2 antibody - ab74861 from Abcam
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Anti-SNT2 antibody - ab38361 from Abcam
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Anti-FRS3 Antibody (aa361-375) - LS-C125627 from LifeSpan Bioscience
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Anti-FRS3 Antibody - LS-C308025 from LifeSpan Bioscience
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Anti-FRS3 Antibody (Phe219) - LS-C340849 from LifeSpan Bioscience
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Anti-FRS3 Antibody (C-Terminus) - LS-C151346 from LifeSpan Bioscience
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Anti-FRS3 Antibody (aa191-240) - LS-C119519 from LifeSpan Bioscience
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Anti-FRS3 Antibody (aa359-408) - LS-C111387 from LifeSpan Bioscience
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FRS3 Antibody - NBP1-83420 from Novus Biologicals
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FRS3 Antibody - NBP1-52962 from Novus Biologicals
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FRS3 Antibody - NBP1-83421 from Novus Biologicals
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FRS3 Antibody - H00010817-B01 from Novus Biologicals
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FRS3 Antibody - H00010817-B01P from Novus Biologicals
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FGFR substrate 3 Polyclonal Antibody - bs-10383R from Bioss
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FGFR substrate 3 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-10383R-A350 from Bioss
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FGFR substrate 3 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-10383R-A488 from Bioss
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FGFR substrate 3 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-10383R-A555 from Bioss
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FGFR substrate 3 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-10383R-A647 from Bioss
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FGFR substrate 3 Polyclonal Antibody, Cy3 Conjugated - bs-10383R-Cy3 from Bioss
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FGFR substrate 3 Polyclonal Antibody, Cy5 Conjugated - bs-10383R-Cy5 from Bioss
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