PTGER4

Gene Symbol	PTGER4
Entrez Gene	5734
Alt Symbol	EP4, EP4R
Species	Human
Gene Type	protein-coding
Description	prostaglandin E receptor 4 (subtype EP4)
Other Description	PGE receptor EP4 subtype|PGE receptor, EP4 subtype|PGE2 receptor EP4 subtype|prostaglandin E2 receptor EP4 subtype|prostanoid EP4 receptor
Swissprots	P35408 Q3MJ87
Accessions	ABD48960 CAA66463 CCF76996 EAW55996 EAW55997 P35408 AY429109 AAR07904 BC027934 AAH27934 BC101534 AAI01535 BC113523 AAI13524 BM312677 BQ029720 CD000197 D28472 BAA05834 HQ258444 ADR83198 L25124 AAA36438 L28175 AAA36434 XM_005248326 XP_005248383 XM_005248327 XP_005248384 XM_011514070 XP_011512372 XM_011514071 XP_011512373 XR_925635 NM_000958 NP_000949
Function	Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Tissue Specificity	High in intestine and in peripheral blood mononuclear cells; low in lung, kidney, thymus, uterus, vasculature and brain. Not found in liver, heart, retina oe skeletal muscle.
Top Pathways	Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Prostaglandin E Receptor EP4 full length protein - ab132115 from Abcam Category Protein Source Wheat germ Species Human

Human Prostaglandin E Receptor EP4 peptide - ab45294 from Abcam Category Peptide

Human Prostaglandin E Receptor EP4 protein fragment - ab152638 from Abcam Category Protein Source Wheat germ Species Human

Prostaglandin E Receptor EP4 peptide (302-314) - ab45876 from Abcam Category Peptide Species Human

PTGER4 / EP4 Antibody Blocking Peptide - LS-E28821 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

PTGER4 / EP4 Antibody Blocking Peptide - LS-E28828 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

PTGER4 / EP4 Antibody Blocking Peptide - LS-E28835 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

PTGER4 / EP4 Antibody Blocking Peptide - LS-E28836 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

PTGER4 / EP4 Antibody Blocking Peptide - LS-E28837 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

PTGER4 / EP4 Antibody Blocking Peptide - LS-E26042 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PTGER4/EP4 Protein - H00005734-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PTGER4/EP4 Partial Recombinant Protein - H00005734-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human PTGER4/EP4 Protein - H00005734-G01 from Novus Biologicals Category Protein Prices $569.00 Sizes 10 µg Source Wheat Germ Species Human

PTGER4 / EP4 blocking peptide - GTX89385-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Dog

EP4 Blocking Peptide - abx063160 from Abbexa Category Peptide Species Human, Monkey

Prostaglandin E Receptor Ep4 Peptide - AC21-0870-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

PTGER4 - H00005734-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

PTGER4 - H00005734-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

PTGER4 - H00005734-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

PTGER4 - H00005734-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PTGER4 - H00005734-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

EP4 Prostaglandin Receptor Peptide - 45-540P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

PTGER4 fusion protein - Ag19262 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

PTGER4 fusion protein - ag19217 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

PTGER4 Peptide - GWB-38WU1H from Genway Biotech Category Peptide Prices $289.00 Sizes 50 µg Source Prostaglandin E receptor EP4 is a Prostanoid Receptor with a relaxing effect on smooth muscle. It may play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

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