PTGER4

Gene Symbol PTGER4
Entrez Gene 5734
Alt Symbol EP4, EP4R
Species Human
Gene Type protein-coding
Description prostaglandin E receptor 4 (subtype EP4)
Other Description PGE receptor EP4 subtype|PGE receptor, EP4 subtype|PGE2 receptor EP4 subtype|prostaglandin E2 receptor EP4 subtype|prostanoid EP4 receptor
Swissprots P35408 Q3MJ87
Accessions ABD48960 CAA66463 CCF76996 EAW55996 EAW55997 P35408 AY429109 AAR07904 BC027934 AAH27934 BC101534 AAI01535 BC113523 AAI13524 BM312677 BQ029720 CD000197 D28472 BAA05834 HQ258444 ADR83198 L25124 AAA36438 L28175 AAA36434 XM_005248326 XP_005248383 XM_005248327 XP_005248384 XM_011514070 XP_011512372 XM_011514071 XP_011512373 XR_925635 NM_000958 NP_000949
Function Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity High in intestine and in peripheral blood mononuclear cells; low in lung, kidney, thymus, uterus, vasculature and brain. Not found in liver, heart, retina oe skeletal muscle.
Top Pathways Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction

EP4 (C-4) - sc-55596 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
EP4 (C-4): sc-55596. Western blot analysis of EP4 expression in HeLa (A), NIH/3T3 (B) and KNRK (C) whole cell lysates.

EP4 (C-18) - sc-16022 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
EP4 (C-18): sc-16022. Immunoperoxidase staining of formalin fixed, paraffin-embedded human thyroid gland tissue showing cytoplasmic staining of glandular cells.

EP4 (H-160) - sc-20677 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
EP4 (H-160): sc-20677. Immunofluorescence staining of normal mouse intestine frozen section showing membrane staining.

Anti-Prostaglandin E Receptor EP4 antibody - ab133170 from Abcam

Prices $378.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin embedded Human prostate tissue labelling Prostaglandin E Receptor EP4 with ab133170 antibody at a concentration of 5 µg/ml, followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-Prostaglandin E Receptor EP4 antibody - ab93486 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Prostaglandin E Receptor EP4 antibody (ab93486) at 1/2000 dilutionLane 1 : IM-9 cell lysate at 43 µgLane 2 : IM-9 cell lysate at 53 µgLane 3 : SGC cell lysate at 43 µgLane 4 : SGC cell lysate at 53 µg

Anti-Prostaglandin E Receptor EP4 antibody - ab45295 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab45295 stained HeLa cells. The cells were 100% methanol fixed (5 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab45295, 5µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM. This antibody also gave a positive result in 4% PFA fixed (5 min) HeLa cells at 5µg/ml.

Anti-Prostaglandin E Receptor EP4 antibody (Phycoerythrin) - ab133716 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PTGER4 / EP4 Antibody (C-Terminus) IHC-plus™ - LS-A3890 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PTGER4 / EP4 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-PTGER4 / EP4 Antibody (2nd Extracellular Domain) - LS-C23117 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-PTGER4 / EP4 Antibody (aa1-23) - LS-C23120 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PTGER4 / EP4 Antibody (C-Terminus) - LS-C23119 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-PTGER4 / EP4 Antibody - LS-C137448 from LifeSpan Bioscience

Prices $265.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PTGER4 / EP4 Antibody (aa313-362) - LS-C200475 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from HeLa cells using PE2R4 antibody.

Anti-PTGER4 / EP4 Antibody IHC-plus™ - LS-B6974 from LifeSpan Bioscience

Prices $395.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-PTGER4 / EP4 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6974 concentration 5 ug/ml.

Anti-PTGER4 / EP4 Antibody (His362) - LS-C177088 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of EP4 (H362) pAb in extracts from COLO205 cells.

Anti-PTGER4 / EP4 Antibody (Internal) - LS-C54789 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (0.1 ug/ml) staining of Human Testes lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-PTGER4 / EP4 Antibody (aa321-370) - LS-C120587 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of MCF7 cells, using PE2R4 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-PTGER4 / EP4 Antibody IHC-plus™ - LS-B6947 from LifeSpan Bioscience

Prices $395.00
Sizes 1 ea
Host Rabbit
Clonality Polyclonal
Anti-PTGER4 / EP4 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6947 concentration 5 ug/ml.

Anti-PTGER4 / EP4 Antibody (aa242-269) - LS-C204013 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PTGER4 Antibody western blot of HL-60,K562 cell line and mouse brain lysates (35 ug/lane). The PTGER4 antibody detected the PTGER4 protein (arrow).

Anti-PTGER4 / EP4 Antibody (C-Terminus) IHC-plus™ - LS-A3896 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human, Colon: Formalin-Fixed Paraffin-Embedded (FFPE)

Anti-PTGER4 / EP4 Antibody (N-Terminus) IHC-plus™ - LS-A3898 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PTGER4 / EP4 antibody LS-A3898 IHC of human colon, ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-PTGER4 / EP4 Antibody (Extracellular Domain) IHC-plus™ - LS-A383 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human, Liver: Formalin-Fixed Paraffin-Embedded (FFPE)

Anti-PTGER4 / EP4 Antibody (C-Terminus) IHC-plus™ - LS-A385 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human, Pancreas: Formalin-Fixed Paraffin-Embedded (FFPE)

PTGER4/EP4 Antibody - NLS3898 from Novus Biologicals

Prices $329.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

PTGER4/EP4 Antibody - NLS3896 from Novus Biologicals

Prices $329.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: PTGER4/EP4 Antibody [NLS3896] - Analysis of anti-PTGER4 antibody with human, colon.
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