PTGER4

Gene Symbol	PTGER4
Entrez Gene	5734
Alt Symbol	EP4, EP4R
Species	Human
Gene Type	protein-coding
Description	prostaglandin E receptor 4 (subtype EP4)
Other Description	PGE receptor EP4 subtype|PGE receptor, EP4 subtype|PGE2 receptor EP4 subtype|prostaglandin E2 receptor EP4 subtype|prostanoid EP4 receptor
Swissprots	P35408 Q3MJ87
Accessions	ABD48960 CAA66463 CCF76996 EAW55996 EAW55997 P35408 AY429109 AAR07904 BC027934 AAH27934 BC101534 AAI01535 BC113523 AAI13524 BM312677 BQ029720 CD000197 D28472 BAA05834 HQ258444 ADR83198 L25124 AAA36438 L28175 AAA36434 XM_005248326 XP_005248383 XM_005248327 XP_005248384 XM_011514070 XP_011512372 XM_011514071 XP_011512373 XR_925635 NM_000958 NP_000949
Function	Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Tissue Specificity	High in intestine and in peripheral blood mononuclear cells; low in lung, kidney, thymus, uterus, vasculature and brain. Not found in liver, heart, retina oe skeletal muscle.
Top Pathways	Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

EP4 CRISPR/Cas9 KO Plasmid (h) - sc-401146 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

EP4 HDR Plasmid (h) - sc-401146-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

EP4 Double Nickase Plasmid (h) - sc-401146-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

EP4 Double Nickase Plasmid (h2) - sc-401146-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

EP4 CRISPR Activation Plasmid (h) - sc-401146-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

EP4 CRISPR Activation Plasmid (h2) - sc-401146-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

EP4 Lentiviral Activation Particles (h) - sc-401146-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

EP4 Lentiviral Activation Particles (h2) - sc-401146-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

EP4 siRNA (h) - sc-40173 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

EP4 shRNA Plasmid (h) - sc-40173-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

EP4 shRNA (h) Lentiviral Particles - sc-40173-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

EP4 siRNA (h2) - sc-270128 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

EP4 shRNA Plasmid (h2) - sc-270128-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

EP4 shRNA (h2) Lentiviral Particles - sc-270128-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PTGER4/EP4 RNAi - H00005734-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU117601 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® esiRNA - EHU031731 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1850 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1850 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09226 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr09226

PTGER4 siRNA (Human) - CRH3878 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human PTGER4 (NM_000958.2) - SHH386012 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human PTGER4(NM_000958.2) - SHR106716 from Creative biogene Category siRNA Species Reactivities Human

Human PTGER4 siRNA - orb264380 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

PTGER4 shRNA Plasmid (Human) - CHH3878 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

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