| Gene Symbol | NOTO |
|---|---|
| Entrez Gene | 344022 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | notochord homeobox |
| Other Description | homeobox protein notochord|notochord homolog |
| Swissprots | A8MTQ0 B4DJ59 B7ZAU5 |
| Accessions | A8MTQ0 AK295936 BAG58721 AK316410 BAH14781 NM_001134462 NP_001127934 |
| Function | Transcription regulator acting downstream of both FOXA2 and T during notochord development. Required for node morphogenesis. Is essential for cilia formation in the posterior notochord (PNC) and for left-right patterning; acts upstream of FOXJ1 and RFX3 in this process and is required for the expression of various components important for axonemal assembly and function. Plays a role in regulating axial versus paraxial cell fate (By similarity). {ECO:0000250}. |
| Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}. |
notochord homeobox, ELISA Kit - MBS9325311 from MyBioSource
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Human NOTO ELISA Kit - E026805 from Biobool
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