Gene Symbol | NOTO |
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Entrez Gene | 344022 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | notochord homeobox |
Other Description | homeobox protein notochord|notochord homolog |
Swissprots | A8MTQ0 B4DJ59 B7ZAU5 |
Accessions | A8MTQ0 AK295936 BAG58721 AK316410 BAH14781 NM_001134462 NP_001127934 |
Function | Transcription regulator acting downstream of both FOXA2 and T during notochord development. Required for node morphogenesis. Is essential for cilia formation in the posterior notochord (PNC) and for left-right patterning; acts upstream of FOXJ1 and RFX3 in this process and is required for the expression of various components important for axonemal assembly and function. Plays a role in regulating axial versus paraxial cell fate (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}. |
NOTO Antibody Blocking Peptide - LS-E13193 from LifeSpan Bioscience
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Recombinant Human Homeobox protein notochord(NOTO) - CSB-YP015954HU CSB-EP015954HU CSB-BP015954HU CSB-MP015954HU from Cusabio
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NOTO Recombinant Protein Antigen - NBP1-91009PEP from Novus Biologicals
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NOTO Peptide, Human - M34GP10519H from Creative Peptides
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Homeobox protein notochord (NOTO), Recombinant Protein - MBS1194019 from MyBioSource
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