WRNIP1

Gene Symbol WRNIP1
Entrez Gene 56897
Alt Symbol WHIP, bA420G6.2
Species Human
Gene Type protein-coding
Description Werner helicase interacting protein 1
Other Description ATPase WRNIP1|Werner helicase-interacting protein 1|putative helicase RUVBL
Swissprots Q59ET8 Q9H681 Q5W0E2 B2RDB0 Q96S55 Q9NRJ6 Q53EP6 Q5W0E4 Q8WV26
Accessions CAT02184 EAW55085 EAW55086 EAW55087 EAW55088 Q96S55 AB056152 BAB60709 AB209723 BAD92960 AF218313 AAF80563 AK026179 BAB15383 AK094823 BAG52937 AK223593 BAD97313 AK315047 AK315471 BAG37857 BC018923 AAH18923 DQ891950 ABM82876 DQ895136 ABM86062 U56249 XM_005249232 XP_005249289 XM_005249234 XP_005249291 NM_020135 NP_064520 NM_130395 NP_569079
Function Functions as a modulator for initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. Has an intrinsic ATPase activity that functions as a sensor of DNA damage or of arrested replication forks and regulates the extent of DNA synthesis. {ECO:0000269|PubMed:15670210}.
Subcellular Location Nucleus {ECO:0000250}. Note=Colocalizes with WRN in granular structures in the nucleus. {ECO:0000250}.
Tissue Specificity Ubiquitously expressed. {ECO:0000269|PubMed:11301316}.

WHIP (N-17) - sc-55437 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
WHIP (N-17): sc-55437. Western blot analysis of WHIP expression in Jurkat (A) and IMR-32 (B) nuclear extracts.

WHIP (G-2) - sc-377402 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
WHIP (G-2): sc-377402. Western blot analysis of WHIP expression in SK-MEL-28 (A) and SJRH30 (B) whole cell lysates.

WHIP (D-20) - sc-55435 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
WHIP (D-20): sc-55435. Western blot analysis of WHIP expression in non-transfected: sc-117752 (A) and mouse WHIP transfected: sc-124643 (B) 293T whole cell lysates.

WHIP (C-20) - sc-55434 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
WHIP (C-20): sc-55434. Western blot analysis of WHIP expression in Jurkat (A) and NCI-H292 (B) whole cell lysates.

WHIP (A-8) - sc-376438 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
WHIP (A-8): sc-376438. Immunoperoxidase staining of formalin fixed, paraffin-embedded human thyroid gland tissue showing nuclear staining of glandular cells.

WHIP (H-300) - sc-134917 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
WHIP (H-300): sc-134917. Western blot analysis of WHIP expression in non-transfected: sc-117752 (A) and mouse WHIP transfected: sc-124643 (B) 293T whole cell lysates.

WHIP (K-20) - sc-55436 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
WHIP (K-20): sc-55436. Western blot analysis of WHIP expression in Jurkat (A), Hep G2 (B) and NCI-H292 (C) whole cell lysates.

WHIP (A-7) - sc-271637 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
WHIP (A-7): sc-271637. Western blot analysis of WHIP expression in non-transfected: sc-117752 (A) and mouse WHIP transfected: sc-124643 (B) 293T whole cell lysates.

Anti-WHIP antibody - ab99316 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human ovarian carcinoma tissue labelling WHIP with ab99316 at 1/1000 (1µg/ml). Detection: DAB.

Anti-WHIP antibody - ab115534 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Kidney (formalin-fixed, paraffin-embedded) stained with ab115534 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-WHIP antibody - ab4731 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-WHIP antibody - ab126059 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-WHIP antibody (ab126059) at 1/1000 dilution + A431 cell lysate at 30 µg

Anti-WHIP antibody - ab84475 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab84475, at a 1/250 dilution, staining WHIP in formalin fixed, paraffin embedded human breast carcinoma section by Immunohistochemistry . Detection: DAB staining.

Anti-WHIP antibody - ab18729 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
ab18729 (4µg/ml) staining of paraffin embedded Human Kidney following steamed antigen retrieval with Tris/EDTA buffer pH 9 and HRP-staining shows nuclear staining, stronger in DCT compared to PCT.

Anti-WHIP antibody - N-terminal - ab138866 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-WHIP antibody - N-terminal (ab138866) at 1/100 dilution + NCI-H292 cell line lysate at 35 µg

Anti-WRNIP1 / WHIP Antibody (aa1-30, FITC) - LS-C242783 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-WRNIP1 / WHIP Antibody (aa1-30, Biotin) - LS-C242782 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-WRNIP1 / WHIP Antibody (aa1-30, APC) - LS-C242781 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-WRNIP1 / WHIP Antibody (aa652-665) - LS-C55687 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-WRNIP1 / WHIP Antibody (aa1-30, PE) - LS-C242786 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-WRNIP1 / WHIP Antibody (aa1-30, AP) - LS-C242780 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-WRNIP1 / WHIP Antibody (aa1-30, Azide-free, HRP) - LS-C247259 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-WRNIP1 / WHIP Antibody (aa1-30) - LS-C326376 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-WRNIP1 / WHIP Antibody - LS-C155277 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate) A: A431 7.5% SDS PAGE WRNIP1 / WHIP antibody diluted at 1:1000

Anti-WRNIP1 / WHIP Antibody (aa400-450) - LS-C288184 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human WRNIP1 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-WRNIP1 used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.
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